Antibiotic (Penicillin)
Brand of Phenoxymethylpenicillin
Last reviewed June 2026
Who is this for?
Phenoxymethylpenicillin (also called Penicillin V) is an antibiotic that works by killing bacteria responsible for infections. It stops bacteria from building their protective walls, which causes them to die off.
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and preventing peptidoglycan cross-linking, leading to bacterial cell lysis and death. Bactericidal activity is effective against susceptible gram-positive cocci, particularly streptococci responsible for respiratory and oral infections.
Prescription Required
You need a doctor's prescription to buy this drug.
Is Phenoxymethylpenicillin safe to take with another drug?
Check with multiple drugs →Explore this drug
Adults usually take 250 mg to 500 mg (1 to 2 tablets) every 6 hours, meaning 4 times a day. Take it on an empty stomach — at least 30 minutes before food or 2 hours after eating — so your body absorbs it better. Swallow with a full glass of water and complete the entire course your doctor or pharmacist prescribed, even if you feel better.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take a double dose to make up for the one you missed.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always complete the full course of this antibiotic even if you feel better after a few days — stopping early can cause the infection to come back stronger and harder to treat. Buy only from licensed pharmacies, not roadside vendors or open markets, as fake or expired antibiotics are common. Do not share your antibiotics with anyone else, even if they have similar symptoms.
Methotrexate (used for arthritis and some cancers) — penicillin can increase its side effects. Warfarin (blood-thinning medicine) — penicillin may increase bleeding risk, so inform your doctor. Some contraceptive pills may become less effective while taking this antibiotic, so use additional protection during the course.
Check your specific combination
Is it safe to take Phenoxymethylpenicillin with your other drugs?
Phenoxymethylpenicillin is generally considered safe during pregnancy and breastfeeding, but you should always consult your doctor before taking it to be sure it is right for your situation.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing near windows or in cars. Keep tablets in their original container. If using the liquid suspension, store it in a refrigerator after mixing and use within 7 to 14 days. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Phenopen-V 250 mg Tablet
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NAFDAC Number
A11-0448
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