Corticosteroid (steroid anti-inflammatory)
Brand of Dexamethasone
Last reviewed June 2026
Who is this for?
Dexamethasone is a strong steroid medicine that works by reducing inflammation (swelling), calming down your immune system, and helping your body handle serious allergic reactions and other conditions.
Binds to glucocorticoid receptors in the cytoplasm, translocates to the nucleus, and suppresses the transcription of pro-inflammatory cytokines (IL-1, IL-6, TNF-α) and adhesion molecules, thereby reducing inflammation, immune response, and vascular permeability across multiple tissues.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take the tablet with food or milk to reduce stomach upset. Your doctor will tell you the exact dose — it varies widely depending on your condition. For most conditions, adults start with 0.5 mg to 9 mg daily, taken once in the morning or split into 2-3 doses. Never start or stop this drug on your own — your doctor may need to reduce your dose slowly before you stop.
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two doses at once to make up for the one you missed.
Do not buy dexamethasone from roadside sellers or use it without a doctor's prescription — misuse of steroids is very common in Nigeria and can cause serious harm including diabetes, weak bones, and a weakened immune system. Never stop taking this drug suddenly if you have been using it for more than a few days — your doctor must reduce the dose gradually. Some people in Nigeria mix dexamethasone into herbal concoctions to make them seem effective — avoid any unmarked or unregistered medicines.
Avoid taking with NSAIDs like ibuprofen or diclofenac as this greatly increases the risk of stomach ulcers and bleeding. If you are taking medicines for diabetes (like metformin or glibenclamide), dexamethasone can raise your blood sugar and your doctor may need to adjust your dose. Alcohol should be avoided as it increases the risk of stomach problems.
Check your specific combination
Is it safe to take Dexamethasone with your other drugs?
Dexamethasone is not safe to use during pregnancy or breastfeeding unless your doctor specifically prescribes it for a serious condition — always consult your doctor first.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be hot, so avoid leaving it near windows or in your car. Keep the tablets in their original container and always store out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for P-ONE Dexamethasone Tablets 0.5 mg
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NAFDAC Number
A4-6659
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