Antibiotic (Cephalosporin + Beta-lactamase inhibitor)
Brand of Ceftriaxone; Sulbactam
Last reviewed June 2026
NAFDAC registration currently inactive
This product's NAFDAC registration is not currently active. It may still be available in pharmacies, but you should verify its status with your pharmacist before use.
Verify on NAFDAC Greenbook →Who is this for?
This is a combination antibiotic injection that contains ceftriaxone (which kills bacteria) and sulbactam (which stops bacteria from resisting the antibiotic). Together, they fight a wider range of infections more effectively than ceftriaxone alone.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
This is not a tablet — it must be given as an injection by a trained healthcare worker. The usual adult dose is 1 g ceftriaxone + 500 mg sulbactam (1.5 g total) given once or twice daily, depending on how serious the infection is. Your doctor will decide the exact dose and whether it goes into your muscle or vein.
Since this injection is given by a healthcare professional, try to keep all your appointment times. If you miss a scheduled dose, contact your doctor or hospital immediately so they can reschedule it. Do not try to double up on doses.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always complete the full course of injections your doctor prescribed, even if you feel better — stopping early can make the infection come back stronger. Only get this injection at a hospital, clinic, or from a qualified health worker — never buy and inject yourself at home. Do not buy from roadside sellers or unregistered pharmacies, as fake antibiotics are common in Nigeria.
Do not mix or use together with calcium-containing drips (like Ringer's lactate) as it can form dangerous crystals in the body. Blood thinners like warfarin may become stronger when used with this drug, increasing bleeding risk. Inform your doctor if you are taking any other antibiotics or medications.
Check your specific combination
Is it safe to take Ceftriaxone with your other drugs?
Consult your doctor before using this injection if you are pregnant or breastfeeding — it should only be used if the doctor decides the benefit outweighs the risk.
Store the unopened powder in a cool, dry place below 30°C — away from direct sunlight and humidity. Once mixed with water for injection, use it immediately or within the time your pharmacist advises. Always keep away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Annxone-S Powder for Injection
Packaging image coming soon
We're building our packaging database — check back soon
NAFDAC Number
B4-9247
Verify Your Pack