MyHep DVIR Tablets Tablet (Sofosbuvir; Daclatasvir) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Sofosbuvir/Daclatasvir is a combination of two antiviral medicines that work together to stop the hepatitis C virus from multiplying in your body, helping your liver heal and clearing the virus from your blood.

What is it used for?

Chronic hepatitis C infection (long-term liver infection caused by the hepatitis C virus)

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Hepatitis B & C Chickenpox & Shingles

How it works

Inhibits hepatitis C virus (HCV) replication by dual mechanism: sofosbuvir acts as a nucleotide analog inhibiting the viral NS5B RNA-dependent RNA polymerase, while daclatasvir binds to and inhibits the viral NS5A protein, preventing viral RNA replication and virion assembly.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Take one tablet of Sofosbuvir (400mg) and one tablet of Daclatasvir (60mg) together once daily, with or without food. The usual treatment lasts 12 weeks, but your doctor may extend it to 24 weeks depending on your condition. Swallow the tablets whole with water — do not crush or chew them. In Nigeria, you may find this as MyHep DVIR Tablets.

What if I Miss a Dose?

If you miss a dose and it is less than 18 hours late, take it as soon as you remember. If it is more than 18 hours late, skip the missed dose and take the next one at your regular time. Do not take two doses at once to make up for the missed one.

What to watch out for

You must complete the full 12 or 24 weeks of treatment even if you feel fine — stopping early means the virus can come back and become harder to treat. Only buy from licensed pharmacies and verified sources, as fake hepatitis C medicines are common in Nigeria. Do not share your medication with another person even if they also have hepatitis C, as their treatment plan may be different.

Common Side Effects

Headache
tiredness or feeling weak
feeling sick to your stomach (nausea)
trouble sleeping
and loss of appetite

Serious Side Effects

Slow heartbeat or feeling like your heart is beating irregularly (especially if you take heart medicines like amiodarone)
severe skin rash or swelling of the face and throat
and signs of liver problems like yellowing of the eyes
dark urine
or unusual stomach pain — see a doctor immediately if any of these happen.

Drug Interactions

Do not take with amiodarone (a heart medicine) as it can cause dangerously slow heartbeat. Avoid using with rifampicin (commonly used to treat TB in Nigeria) or St. John's Wort, as these can reduce the effectiveness of the medicine. Avoid alcohol completely during treatment, as it damages the liver and works against your treatment.

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Is it safe to take Sofosbuvir; with your other drugs?

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Pregnancy & Breastfeeding Warning

This combination is not recommended during pregnancy or breastfeeding — consult your doctor before starting treatment if you are pregnant, planning to become pregnant, or breastfeeding.

Who Should NOT Take This

People allergic to sofosbuvir or daclatasvir
those currently taking amiodarone or rifampicin
patients with severe liver damage (decompensated liver disease) unless under specialist care
and children under 18 years old.

How to Store

Store at room temperature below 30°C in a cool, dry place away from direct sunlight and humidity. Keep the tablets in their original packaging and far from the reach of children. In hot Nigerian weather, avoid storing medicines in cars or near windows.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

MyHep DVIR Tablets