Antibiotic (Penicillin)
Brand of Procaine Benzylpenicillin; Benzylpenicillin Sodium
Last reviewed June 2026
Who is this for?
This is a combination antibiotic injection containing two forms of penicillin — Procaine Benzylpenicillin (a slow-release form) and Benzylpenicillin Sodium (a fast-acting form). Together, they quickly kill bacteria and keep working in your body for a longer time.
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and preventing cross-linking of peptidoglycan, resulting in cell wall degradation and bactericidal activity against susceptible Gram-positive and Gram-negative bacteria.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
This drug is given as an injection into the muscle (usually the buttocks) by a nurse, doctor, or trained health worker — it is NOT for self-administration. Adults typically receive 1 to 4 million units once or twice daily depending on the type and severity of infection. Your doctor will decide the exact dose and how many days you need it. Always complete the full course even if you feel better.
If you miss a scheduled injection, go to your hospital or clinic as soon as possible to get it. Do not try to double up. Missing doses of antibiotics can make the infection harder to treat, so try to keep all your appointments.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always get this injection from a licensed hospital, clinic, or pharmacy — never from roadside sellers or unqualified persons, as fake or expired injections are dangerous. Complete the full course of treatment your doctor prescribed even if you feel better after one or two injections — stopping early can cause the infection to come back stronger. Watch for any signs of allergic reaction for at least 30 minutes after each injection.
Methotrexate (used for arthritis or cancer) — penicillin can increase its side effects. Probenecid (used for gout) — can increase penicillin levels in the blood. Blood thinners like warfarin — penicillin may increase bleeding risk. Let your doctor know all medications you are currently taking.
Check your specific combination
Is it safe to take Procaine with your other drugs?
Penicillin is generally considered safe during pregnancy and breastfeeding, but always inform your doctor that you are pregnant or breastfeeding before receiving this injection.
Store the powder in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing near windows or in cars. Once mixed with water, use it immediately or within a few hours as directed. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Procaine Penicillin 3,000,000 IU, Benzyl Penicillin Sodium 1,000,000 IU
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NAFDAC Number
B4-7615
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