Antimalarial
Brand of Chloroquine
Last reviewed June 2026
Who is this for?
Chloroquine is an antimalarial drug that works by killing the malaria parasite inside your red blood cells, stopping the infection from spreading in your body.
Inhibits Plasmodium parasite growth by accumulating in the parasite's digestive vacuole and intercalating into parasite DNA, disrupting nucleic acid synthesis and increasing local pH to toxic levels. Additionally, suppresses inflammatory responses by inhibiting toll-like receptor signaling and reducing pro-inflammatory cytokine production, making it effective in autoimmune conditions.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For malaria treatment in adults, the usual dose is 4 tablets (600mg base) on Day 1, then 2 tablets (300mg base) after 6-8 hours on the same day, then 2 tablets on Day 2, and 2 tablets on Day 3. Take with food or a glass of water to reduce stomach upset. Always complete the full course even if you start feeling better.
If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed one and continue your normal schedule. Do not take a double dose to make up for it.
In Nigeria, chloroquine resistance is now very common — if your malaria does not improve within 2-3 days, go back to the hospital as you may need a different drug like ACTs (Artemisinin-based combination therapy). Do not buy chloroquine from roadside sellers or unregistered vendors as fake and expired drugs are common. The itching some Nigerians experience can be intense but is usually not dangerous — do not stop the medication without talking to your pharmacist or doctor.
Do not take chloroquine with antacids like magnesium hydroxide (Gestid, Andrews) at the same time — they reduce how well chloroquine works; take them at least 4 hours apart. Be careful if you are taking heart drugs like digoxin, as chloroquine can increase its effects dangerously. Avoid drinking alcohol while on chloroquine as it can worsen dizziness and stomach upset.
Check your specific combination
Is it safe to take Chloroquine with your other drugs?
Chloroquine is generally considered safer than many other antimalarials during pregnancy, but you should always consult your doctor before taking it if you are pregnant or breastfeeding.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing near windows or in your car. Keep the container tightly closed and always keep it far away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Fexona Chloroquine 40 mg/mL Injection
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NAFDAC Number
B4-6736
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