Antibiotic (Penicillin combination with beta-lactamase inhibitor)
Brand of Amoxicillin; Clavulanic Acid
Last reviewed June 2026
Who is this for?
This is a combination antibiotic that pairs amoxicillin (which kills bacteria) with clavulanic acid (which stops bacteria from defending themselves against the amoxicillin). Together, they work as a stronger team to fight infections that regular amoxicillin alone cannot handle.
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and preventing peptidoglycan cross-linking; clavulanic acid irreversibly inhibits bacterial beta-lactamases, preventing enzymatic degradation of amoxicillin and restoring its efficacy against resistant organisms.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For adults, the usual dose is one 625 mg tablet twice or three times daily, or one 1000 mg (1G) tablet twice daily depending on how serious the infection is. Always take it with food or just before eating — this helps your stomach handle the medicine better and helps your body absorb it well. Swallow the tablet whole with a full glass of water. Complete the full course your pharmacist or doctor prescribed, even if you feel better after a few days.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two doses at once to make up for it.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always complete the full course of this antibiotic even if you feel better — stopping early helps bacteria become resistant, and drug-resistant infections are a growing problem in Nigeria. Buy only from licensed pharmacies and check the NAFDAC number on the pack — do not buy from roadside vendors or open markets where storage conditions are poor. Do not share your antibiotics with family or friends, even if they have similar symptoms — the wrong dose or wrong drug can be dangerous.
Avoid taking it with blood-thinning drugs like warfarin without your doctor knowing, as it can increase your risk of bleeding. If you are taking methotrexate (used for arthritis or cancer), this drug can increase its side effects. It may reduce the effectiveness of birth control pills, so use an additional method like condoms during your course. Alcohol can worsen stomach side effects, so it is best to avoid drinking while on this medication.
Check your specific combination
Is it safe to take Amoxicillin with your other drugs?
Consult your doctor before taking this drug if you are pregnant or breastfeeding — it is generally considered relatively safe, but your doctor should decide if it is necessary for your specific situation.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing near windows or in your car. Keep the suspension (syrup) in the refrigerator after mixing and use it within 7 days. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Myclav 228.5
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NAFDAC Number
B4-6040
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