How do you take Pregabalin; Methylcobalamin?

Usually taken as 1 capsule twice daily (morning and night), with or without food. Your doctor will decide whether you need the 75mg or 150mg strength based on your condition. Swallow the capsule whole with water, do not crush or open it. Always follow your doctor's specific instructions.

What are the side effects of Pregabalin; Methylcobalamin?

Feeling sleepy or drowsy, dizziness or lightheadedness, slight weight gain, dry mouth, mild swelling in the hands or feet

Who should not take Pregabalin; Methylcobalamin?

People who are allergic to Pregabalin or Methylcobalamin, pregnant or breastfeeding women, children under 18, people with severe kidney problems, and anyone with a history of drug or substance abuse should avoid this medicine unless cleared by a doctor.

Prescription

Nerve pain reliever (Neuropathic pain agent) with Vitamin B12 supplement

Pregabalin; Methylcobalamin

Q: What is Pregabalin; Methylcobalamin used for?

Nerve pain (the kind that feels like burning, tingling, or numbness in hands and feet), diabetic nerve damage, back pain with nerve involvement, numbness and tingling sensations

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

This is a combination of two medicines: Pregabalin (which calms overactive nerves and reduces pain signals in the body) and Methylcobalamin (a form of Vitamin B12 that helps repair and protect damaged nerves). Together, they work to reduce nerve pain and help nerves heal.

How it works

Binds to alpha-2-delta subunit of voltage-gated calcium channels, reducing calcium influx and excitatory neurotransmitter release in the dorsal horn of the spinal cord, while methylcobalamin replenishes vitamin B12 to support myelin formation and nerve function restoration.

What is it used for?

Nerve pain (the kind that feels like burningtinglingor numbness in hands and feet)diabetic nerve damageback pain with nerve involvementnumbness and tingling sensations

Browse by condition

Pain Relief Nerve Pain Epilepsy & Seizures Vitamins & Supplements

Prescription Required

You need a doctor's prescription to buy this drug.

Quick Interaction Check

Is Pregabalin; safe to take with another drug?

Check with multiple drugs →

Explore this drug

What to watch out for

This medicine can make you very drowsy, so do not drive, operate machinery, or do anything that requires full alertness until you know how it affects you. Do not stop taking it suddenly without your doctor's advice, as this can cause withdrawal symptoms like headaches, sleep problems, and anxiety. Only buy from trusted pharmacies: brands like Neuracalm 75, Neuracalm 150, or Syrenev Plus are available in Nigeria; avoid unregistered products from roadside sellers.

Common Side Effects

Feeling sleepy or drowsy
dizziness or lightheadedness
slight weight gain
dry mouth
mild swelling in the hands or feet

Serious Side Effects

Severe allergic reaction such as swelling of the face
lips
or throat and difficulty breathing: go to the hospital immediately. Unusual mood changes
thoughts of harming yourself
or severe confusion: stop the drug and see your doctor right away. Blurred vision or difficulty seeing clearly that does not go away.

Drug Interactions

Avoid drinking alcohol while taking this medicine as it can make the drowsiness and dizziness much worse. Be careful if you are taking other painkillers like tramadol or sedatives, as the combined drowsiness can be dangerous. If you are on blood pressure medicines, let your doctor know as the combination may cause extra dizziness.

Check your specific combination

Is it safe to take Pregabalin; with your other drugs?

Check →

Pregnancy & Breastfeeding Warning

This medicine is not considered safe during pregnancy or breastfeeding, so do not use it unless your doctor specifically tells you it is necessary.

Who Should NOT Take This

People who are allergic to Pregabalin or Methylcobalamin
pregnant or breastfeeding women
children under 18
people with severe kidney problems
and anyone with a history of drug or substance abuse should avoid this medicine unless cleared by a doctor.

How to Store

Store in a cool, dry place below 30°C, away from direct sunlight and humidity. Nigerian heat can spoil medicines quickly, so avoid storing in hot places like inside your car or near a window. Always keep out of reach of children.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.