Biologic (TNF-alpha inhibitor / Immunosuppressant)
Last reviewed July 2026
Who is this for?
Golimumab (sold as Simponi in Nigeria) is an injection that works by blocking a substance in your body called TNF-alpha, which causes inflammation and swelling. By blocking this substance, it helps calm down an overactive immune system that is attacking your own body.
Binds to and neutralizes tumour necrosis factor-alpha (TNF-α), blocking its interaction with TNF receptors and suppressing the inflammatory cascade responsible for joint destruction and systemic inflammation in autoimmune and inflammatory conditions.
Rheumatoid arthritis (joint pain and swelling), psoriatic arthritis (joint pain with skin rashes), ankylosing spondylitis (severe back stiffness and pain), ulcerative colitis (long-term stomach pain with bloody stool)
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss your monthly injection and remember within 2 weeks, take it as soon as you remember, then continue your normal schedule. If it is more than 2 weeks late, contact your doctor for advice on when to take the next dose.
This is a specialist drug; only use it if prescribed and monitored by a qualified rheumatologist or specialist doctor, not a general chemist. Because it lowers your immune system, avoid close contact with people who have infections like TB, which is common in Nigeria. Always buy Simponi from reputable hospital pharmacies; never buy from unregistered sellers, as this drug must be kept cold at all times.
Do not take golimumab with other strong immune-suppressing biologics like adalimumab, infliximab, or anakinra as this greatly increases your risk of serious infections. Live vaccines (like yellow fever vaccine) should be avoided while on this drug; tell your doctor before any vaccination. Alcohol should be limited as it can stress the liver.
Check your specific combination
Is it safe to take Golimumab with your other drugs?
Golimumab is not recommended during pregnancy or breastfeeding unless your doctor says the benefit clearly outweighs the risk, so always consult your doctor before use.
Store in a refrigerator (2°C to 8°C). Do not freeze it. Keep it in its original carton to protect it from light. In Nigeria's hot weather, do not leave it outside the fridge as it will spoil quickly. Keep far away from children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.