Antihistamine and cough suppressant combination · Syrup · 2026
This is a combination medicine containing diphenhydramine (an antihistamine that helps stop coughing and dries up runny nose) and sodium citrate (which helps loosen thick mucus in the chest so you can cough it out more easily). Together they work to calm coughs and clear chest congestion.
Exiplon Cough Syrup for Children is a brand of Diphenhydramine HCl; Sodium citrate.
Blocks H1 histamine receptors to reduce allergic symptoms and suppresses the cough reflex via central nervous system depression; sodium citrate acts as an expectorant to facilitate mucus clearance and reduce airway irritation associated with upper respiratory congestion.
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Antihistamine and cough suppressant combination
Brand of Diphenhydramine HCl; Sodium citrate
Last reviewed June 2026
This is a combination medicine containing diphenhydramine (an antihistamine that helps stop coughing and dries up runny nose) and sodium citrate (which helps loosen thick mucus in the chest so you can cough it out more easily). Together they work to calm coughs and clear chest congestion.
Blocks H1 histamine receptors to reduce allergic symptoms and suppresses the cough reflex via central nervous system depression; sodium citrate acts as an expectorant to facilitate mucus clearance and reduce airway irritation associated with upper respiratory congestion.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Is Diphenhydramine safe to take with another drug?
Check with multiple drugs →Explore this drug
Since this medicine is usually taken only when you have symptoms, there's no strict schedule. If you forget a dose, just take it when you remember. But if it's almost time for your next dose, skip the missed one — never double up.
This medicine causes drowsiness — do not drive, operate machines, or do anything requiring alertness after taking it. Buy only from reputable pharmacies and check the expiry date — avoid buying cough syrups from roadside vendors or open markets as they may be fake or expired. If your child's cough lasts more than 5-7 days or gets worse, see a doctor instead of just increasing the dose.
Avoid drinking alcohol while using this medicine as it will make you very drowsy and dizzy. Do not combine with other cough or cold medicines containing antihistamines (like chlorpheniramine or promethazine) as this can cause dangerous over-sedation. If you are taking medicines for anxiety, depression, or sleep, talk to your doctor or pharmacist first.
Check your specific combination
Is it safe to take Diphenhydramine with your other drugs?
Consult your doctor before using this medicine if you are pregnant or breastfeeding — it is not confirmed safe and the drowsiness effect can pass to your baby.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be hot, so avoid leaving it on windowsills or in cars. Keep the bottle tightly closed after use. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Genuine packaging for Exiplon Cough Syrup for Children
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NAFDAC Number
04-7472
Verify Your Pack
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.