Vaxcel Ceftazidime 1 g Injection

Who is this for?

Ceftazidime is a strong antibiotic that works by killing bacteria responsible for serious infections in your body. It belongs to the cephalosporin family of antibiotics and is given as an injection because it works faster and stronger that way.

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and preventing peptidoglycan cross-linking, resulting in bactericidal activity against gram-negative organisms, gram-positive cocci, and anaerobes commonly associated with severe infections.

Is Ceftazidime safe to take with another drug?

This drug is given as an injection into a vein (IV) or muscle (IM) by a doctor or nurse — do not try to inject yourself at home. The usual adult dose is 1g to 2g every 8 to 12 hours depending on how serious the infection is. Your doctor will decide the exact dose and how long you need it, usually 7 to 14 days.

Since this drug is usually given by a healthcare worker on a schedule, a missed dose should be given as soon as possible. Tell your nurse or doctor immediately if you think a dose was skipped so they can adjust your schedule. Do not double up on doses.

• Pain
• redness or swelling at the injection site
• diarrhoea or loose stool
• nausea or vomiting
• rash or itching on the skin

Aminoglycoside antibiotics (like gentamicin) — when used together, your doctor needs to monitor your kidneys closely. Blood thinners like warfarin — ceftazidime may increase bleeding risk, so your doctor should check your blood clotting. Chloramphenicol — may reduce how well ceftazidime works and should generally not be combined.

Store the powder (before mixing) in a cool, dry place below 30°C — away from direct sunlight and humidity, which is important in Nigeria's hot climate. Once mixed with water for injection, use it within the time your pharmacist specifies (usually within 24 hours if refrigerated). Always keep out of reach of children.