Combination: Corticosteroid, Antifungal, and Antibiotic (topical)
Last reviewed July 2026
Who is this for?
This is a combination cream that contains three active ingredients: betamethasone (a steroid that reduces swelling, redness, and itching), clotrimazole (an antifungal that kills fungus), and neomycin (an antibiotic that kills bacteria). Together, they treat skin infections that involve inflammation, fungus, and bacteria at the same time.
Inhibits fungal ergosterol synthesis (clotrimazole), suppresses inflammatory response via glucocorticoid receptor activation (betamethasone), and disrupts bacterial protein synthesis by binding to the 30S ribosomal subunit (neomycin sulfate), providing synergistic antimicrobial and anti-inflammatory action against infected dermatological conditions.
Skin rashes with fungal and bacterial infection, eczema with infection, ringworm with inflammation, itchy skin infections, infected dermatitis
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you forget to apply the cream, apply it as soon as you remember. If it is almost time for your next application, skip the missed one and continue as normal. Do not apply double the amount to make up for the missed dose.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Do not use this cream for longer than your doctor prescribed, as using steroid creams for too long can permanently damage your skin and make it very thin. Do not buy from roadside sellers or use someone else's prescription cream, as the wrong treatment can worsen your skin problem. This cream is popular in Nigeria under brands like Bactineal Cream, 3K Cream, and Arigold, so always make sure you buy from a licensed pharmacy and check the expiry date.
Avoid using other steroid creams or medicated skin products on the same area at the same time unless your doctor says so. If you are taking any oral steroid medications like prednisolone, tell your doctor before using this cream. Do not mix with other antifungal or antibiotic creams on the same spot.
Check your specific combination
Is it safe to take Betamethasone; with your other drugs?
Do not use this cream during pregnancy or while breastfeeding unless your doctor specifically approves it, as the steroid and antibiotic components may pose risks to the baby.
Store below 25°C in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the tube tightly closed after use. Keep out of reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.