How do you take Betamethasone; Clotrimazole; Gentamicin?

Apply a thin layer of the cream to the affected skin area two times a day: morning and night. Gently rub it in. Wash and dry the area before applying. Do not cover the area with a tight bandage unless your doctor says so. Most treatments last 2 to 4 weeks, so do not use it longer than your doctor recommends.

What are the side effects of Betamethasone; Clotrimazole; Gentamicin?

Mild burning or stinging when you first apply it, skin dryness or peeling, itching at the application site, slight skin thinning if used for a long time, lightening of the skin around the treated area

Who should not take Betamethasone; Clotrimazole; Gentamicin?

Do not use this cream if you are allergic to betamethasone, clotrimazole, gentamicin, or any steroid or antibiotic cream. Avoid if you have untreated viral skin infections like chicken pox or cold sores, tuberculosis of the skin, or acne. Do not use on open wounds or broken skin. Not recommended for children under 2 years without a doctor's prescription.

Prescription

Combination: Corticosteroid, Antifungal, and Antibiotic (topical)

Betamethasone; Clotrimazole; Gentamicin

Q: What is Betamethasone; Clotrimazole; Gentamicin used for?

Skin rashes with infection, eczema with fungal or bacterial infection, ringworm with inflammation, stubborn body rash, infected skin patches, jock itch with bacterial infection, nappy rash with infection

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

This is a combination cream that contains three active ingredients: betamethasone (a steroid that reduces swelling and itching), clotrimazole (an antifungal that kills fungal infections), and gentamicin (an antibiotic that kills bacteria). Together, they treat skin conditions that involve inflammation, fungal infection, and bacterial infection at the same time.

How it works

Inhibits fungal ergosterol synthesis and bacterial protein synthesis while suppressing inflammatory cytokine production via glucocorticoid receptor activation, providing simultaneous antifungal, antibacterial, and anti-inflammatory effects on infected skin lesions.

What is it used for?

Skin rashes with infectioneczema with fungal or bacterial infectionringworm with inflammationstubborn body rashinfected skin patchesjock itch with bacterial infectionnappy rash with infection

Browse by condition

Fungal Infections Skin Infections Eczema & Skin Rashes STIs & Sexual Health Sepsis & Severe Infections Fungal Skin Infections

Prescription Required

You need a doctor's prescription to buy this drug.

Quick Interaction Check

Is Betamethasone; safe to take with another drug?

Check with multiple drugs →

Explore this drug

What to watch out for

Do not use this cream as a skin-lightening or toning cream. Many Nigerians misuse steroid creams for bleaching, which causes serious long-term skin damage. Complete the full course your doctor prescribed even if the rash looks better, otherwise the infection can come back stronger. Buy only from a licensed pharmacy, and avoid roadside sellers or open market products as they may be fake or expired.

Common Side Effects

Mild burning or stinging when you first apply it
skin dryness or peeling
itching at the application site
slight skin thinning if used for a long time
lightening of the skin around the treated area

Serious Side Effects

If you notice stretch marks
severe skin thinning
or unusual swelling at the application site
stop using it and see a doctor immediately. Allergic reactions like severe rash
difficulty breathing
or swelling of the face and throat require emergency medical attention.

Drug Interactions

Avoid using other steroid creams or medicated skin products on the same area at the same time as this can increase side effects. Do not mix with skin-lightening creams or toning lotions, as they may contain steroids or harsh chemicals that can react badly. If you are taking any other medication, let your doctor or pharmacist know.

Check your specific combination

Is it safe to take Betamethasone; with your other drugs?

Check →

Pregnancy & Breastfeeding Warning

This cream is not recommended during pregnancy or breastfeeding unless a doctor specifically prescribes it, as the steroid component can be absorbed through the skin and may affect your baby.

Who Should NOT Take This

Do not use this cream if you are allergic to betamethasone
clotrimazole
gentamicin
or any steroid or antibiotic cream. Avoid if you have untreated viral skin infections like chicken pox or cold sores
tuberculosis of the skin
or acne. Do not use on open wounds or broken skin. Not recommended for children under 2 years without a doctor's prescription.

How to Store

Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the tube tightly closed after use. Store out of reach of children.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.