Silybon 140 Tablets Tablet (Silymarin) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Silymarin is a natural supplement made from milk thistle plant that helps protect and repair your liver by acting as an antioxidant and reducing inflammation in liver cells.

What is it used for?

Liver problemsliver damage from alcohol or chemicalsfatty liver diseasehepatitis supportdrug-induced liver damagegeneral liver protection

Browse by condition

Hepatitis B & C

How it works

Inhibits hepatocellular lipid peroxidation and free radical formation by acting as a potent antioxidant and activating hepatoprotective enzymes (superoxide dismutase, catalase, glutathione S-transferase), while stabilizing hepatocyte cell membranes and promoting regeneration of damaged liver tissue. Additionally, modulates inflammatory pathways and inhibits stellate cell activation, reducing hepatic fibrosis progression.

Available Over The Counter

Get this from any pharmacy or chemist — no prescription needed.

Quick Interaction Check

Is Silymarin safe to take with another drug?

Check with multiple drugs →

Explore this drug

How to take this drug

Take one tablet of 140mg (like Silybon 140) two to three times daily, preferably with meals. Swallow the tablet whole with a full glass of water. Your doctor may adjust your dose depending on how serious your liver condition is.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, just skip the missed one and continue your normal schedule. Do not take two doses at once to make up for it.

What to watch out for

Buy only from reputable pharmacies — brands like Silybon 140 are trusted, so avoid unbranded versions from roadside sellers. Silymarin supports the liver but is not a cure for serious liver diseases like hepatitis B or C — you still need proper medical treatment. Do not use it as an excuse to keep drinking alcohol heavily thinking it will protect your liver.

Common Side Effects

Stomach upset or loose stool
bloating or gas
mild headache
feeling of fullness in the stomach
mild allergic skin rash

Serious Side Effects

Severe allergic reaction with swelling of the face
lips or throat — go to the hospital immediately. Yellowing of the eyes or skin getting worse instead of better — see your doctor right away.

Drug Interactions

Silymarin can affect how your body processes certain drugs like diabetes medications (metformin, glibenclamide), making them stronger or weaker — inform your doctor. It may also interact with blood-thinning drugs like warfarin. Avoid taking it with alcohol as alcohol further damages the liver you are trying to protect.

Check your specific combination

Is it safe to take Silymarin with your other drugs?

Check →

Pregnancy & Breastfeeding Warning

If you are pregnant or breastfeeding, consult your doctor before taking silymarin as there is not enough evidence to confirm it is completely safe.

Who Should NOT Take This

People who are allergic to milk thistle or plants in the same family (like ragweed
daisies
or marigold). People with hormone-sensitive conditions like breast cancer or uterine fibroids should consult their doctor first
as silymarin may have mild hormonal effects.

How to Store

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep the container tightly closed to protect from humidity and always keep it out of reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Silybon 140 Tablets