Liver protectant (Hepatoprotective supplement)
Last reviewed June 2026
Who is this for?
Silymarin is a natural supplement made from milk thistle plant that helps protect and repair your liver by acting as an antioxidant and reducing inflammation in liver cells.
Inhibits hepatocellular lipid peroxidation and free radical formation by acting as a potent antioxidant and activating hepatoprotective enzymes (superoxide dismutase, catalase, glutathione S-transferase), while stabilizing hepatocyte cell membranes and promoting regeneration of damaged liver tissue. Additionally, modulates inflammatory pathways and inhibits stellate cell activation, reducing hepatic fibrosis progression.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
Take one tablet of 140mg (like Silybon 140) two to three times daily, preferably with meals. Swallow the tablet whole with a full glass of water. Your doctor may adjust your dose depending on how serious your liver condition is.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, just skip the missed one and continue your normal schedule. Do not take two doses at once to make up for it.
Buy only from reputable pharmacies — brands like Silybon 140 are trusted, so avoid unbranded versions from roadside sellers. Silymarin supports the liver but is not a cure for serious liver diseases like hepatitis B or C — you still need proper medical treatment. Do not use it as an excuse to keep drinking alcohol heavily thinking it will protect your liver.
Silymarin can affect how your body processes certain drugs like diabetes medications (metformin, glibenclamide), making them stronger or weaker — inform your doctor. It may also interact with blood-thinning drugs like warfarin. Avoid taking it with alcohol as alcohol further damages the liver you are trying to protect.
Check your specific combination
Is it safe to take Silymarin with your other drugs?
If you are pregnant or breastfeeding, consult your doctor before taking silymarin as there is not enough evidence to confirm it is completely safe.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep the container tightly closed to protect from humidity and always keep it out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.