Bulmethazine Injection 25 mg/mL

Who is this for?

Promethazine is an antihistamine that works by blocking a natural substance called histamine in your body. It helps reduce allergic reactions, prevents nausea and vomiting, and can make you feel sleepy, which is why it is sometimes used to help with sleep or calm you down before surgery.

Blocks H1 histamine receptors and muscarinic cholinergic receptors, suppressing allergic responses, nausea, and emesis while producing sedation through central nervous system depression.

Is Promethazine safe to take with another drug?

For allergies: Take one 25 mg tablet at bedtime, or 10-25 mg two to three times daily. For motion sickness: Take 25 mg about 30 minutes to 1 hour before travelling, and repeat every 8-12 hours if needed. For nausea and vomiting: Take 12.5-25 mg every 4-6 hours as needed. You can take it with food to reduce stomach upset. This drug makes you very drowsy, so take it at night if you only need one dose a day.

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, just skip the missed one and continue as normal. Do not take a double dose to make up for the one you missed.

• Feeling very sleepy or drowsy
• dry mouth
• dizziness
• blurred vision
• constipation. The drowsiness is very strong with this drug — avoid driving or operating machines after taking it.

Alcohol: Do not drink alcohol while taking promethazine — it makes the drowsiness much worse and can be dangerous. Tramadol and codeine: Taking promethazine with these painkillers increases the risk of extreme drowsiness, slow breathing, and even death. Other sleeping pills or sedatives (like diazepam): Combining them with promethazine can cause dangerously deep sleep.

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can spoil medicines quickly. Do not store in the bathroom where there is humidity. Keep the bottle or pack tightly closed and always keep it far out of reach of children.