Antibiotic (Penicillin)
Brand of Procaine Penicillin; Benzyl Penicillin Sodium
Last reviewed April 2026
Who is this for?
This is a combination antibiotic injection that contains two forms of penicillin — Procaine Penicillin (which releases slowly and works over a longer period) and Benzyl Penicillin Sodium (which works fast). Together, they kill bacteria causing infections by breaking down their protective walls.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
This drug is given as an injection into the muscle (usually the buttocks) by a healthcare professional — do not try to inject yourself at home. For adults, the usual dose is 1 to 2 mega units (MU) given once or twice daily, depending on the severity of your infection. Your doctor will decide the exact dose and how long you need it.
If you miss a scheduled injection, go to your clinic or hospital as soon as you remember. Do not try to double up. Contact your doctor to reschedule so you stay on track with your treatment.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Always get this injection at a proper hospital, clinic, or pharmacy — never from roadside medicine sellers or unqualified persons, as incorrect injection technique can cause serious complications. Complete the full course of injections your doctor prescribed, even if you feel better — stopping early can make the infection come back stronger. Do not share your prescription or leftover medication with anyone else, even if they have similar symptoms.
Methotrexate (used for arthritis or cancer) — penicillin can increase its toxic effects. Probenecid (used for gout) — increases penicillin levels in the blood, which your doctor may use intentionally. Blood-thinning drugs like warfarin — penicillin may increase bleeding risk, so inform your doctor if you take blood thinners.
Check your specific combination
Is it safe to take Procaine with your other drugs?
Penicillin is generally considered safe during pregnancy and breastfeeding, but always inform your doctor that you are pregnant or breastfeeding before receiving this injection.
Store the powder in a cool, dry place below 25°C — avoid direct sunlight and damp areas, which is important in Nigeria's hot and humid climate. Once mixed with water for injection, use it immediately or within a few hours. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Caine Pen Injection 4 Mega
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NAFDAC Number
A4-3033
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