Decongestant and Antihistamine combination
Brand of Phenylephrine Hydrochloride; Chlorphenamine Maleate
Last reviewed April 2026
Who is this for?
This is a combination medicine containing two active ingredients — phenylephrine (a decongestant that shrinks swollen blood vessels in your nose to help you breathe better) and chlorphenamine (an antihistamine that stops sneezing, runny nose, and watery eyes). Together, they relieve cold and flu symptoms.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
Adults typically take 1 capsule every 4 to 6 hours as needed for cold symptoms, usually not more than 4 times a day. You can take it with or without food, but taking it with a little food may reduce stomach upset. Swallow capsules whole with water — do not crush or chew. Known in Nigeria as Cocoff, Colman Capsules, G. G. Cold Capsules, or Gonekold.
Since this medicine is usually taken only when you have symptoms, there is no strict schedule. If you are taking it regularly and miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one — do not double up.
This medicine causes drowsiness — do not drive, operate machinery, or do anything requiring full alertness after taking it. Buy only from licensed pharmacies, not from roadside vendors or bus sellers, to make sure you are getting genuine products. Do not use this medicine continuously for more than 7 days without seeing a doctor — if your cold is not improving, something else may be going on.
Avoid drinking alcohol while taking this medicine — it makes drowsiness much worse and can be dangerous. Do not take it together with other cold or flu medicines (like Actifed or other antihistamines) as you may double up on ingredients. If you are taking blood pressure medication, talk to your pharmacist first because phenylephrine can raise your blood pressure.
Check your specific combination
Is it safe to take Phenylephrine with your other drugs?
This combination is not recommended during pregnancy or breastfeeding unless a doctor says it is okay — consult your doctor or pharmacist before using it.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the pack tightly closed to protect from humidity. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Realflex

Image not available
Realflex — Reference Image(1/2)
NAFDAC Number
B4-0599
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Authenticity Checklist
If your packaging looks significantly different from this image, do not use the drug and report it below.