Zofdan Tablets 4 mg Tablet (Ondansetron) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Ondansetron is an anti-nausea medicine that works by blocking a chemical called serotonin in your body that triggers vomiting and nausea.

What is it used for?

Nauseavomitingvomiting caused by chemotherapy (cancer treatment)vomiting after surgeryvomiting from radiation therapy

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Nausea & Vomiting Cancer Treatment

How it works

Blocks 5-HT3 (serotonin) receptors on vagal afferent nerves and in the chemoreceptor trigger zone, preventing nausea and vomiting signals from reaching the vomiting centre in the brainstem.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

For adults, the usual dose is 4 mg to 8 mg taken by mouth two to three times daily depending on what your doctor prescribes. You can take it with or without food. If using the orally disintegrating tablet, place it on your tongue and let it dissolve — no need to swallow with water.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two doses at once to make up for the one you missed.

What to watch out for

Only buy from licensed pharmacies — avoid buying ondansetron from roadside sellers or unregistered shops as fake drugs are common in Nigeria. Do not use this medicine to treat ordinary stomach upset without a doctor's advice. If vomiting persists after using ondansetron, see a doctor — it could be a sign of something more serious.

Common Side Effects

Headache
constipation (difficulty passing stool)
feeling tired or dizzy
diarrhea

Serious Side Effects

Irregular or fast heartbeat — go to the hospital immediately. Severe allergic reaction such as swelling of the face
tongue
or throat and difficulty breathing — seek emergency help. Blurred vision or sudden chest pain should also be reported to your doctor right away.

Drug Interactions

Apomorphine (used for Parkinson's disease) should never be taken with ondansetron as it can cause a dangerous drop in blood pressure. Tramadol — ondansetron may reduce the pain-relieving effect of tramadol. Also be cautious if you are taking other medicines that affect heart rhythm, and mention all your medications to your pharmacist or doctor.

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Pregnancy & Breastfeeding Warning

Ondansetron should be used during pregnancy and breastfeeding only if your doctor says the benefit outweighs the risk — always consult your doctor before taking it if you are pregnant or nursing.

Who Should NOT Take This

People who are allergic to ondansetron or any of its ingredients
people taking apomorphine
people with a heart condition called congenital long QT syndrome (a problem with the heart's electrical activity)
and people with severe liver problems should avoid this drug or use it only under close medical supervision.

How to Store

Store at room temperature, away from direct sunlight and heat — Nigerian weather can be very hot, so don't leave it in your car or near a window. Keep it in a cool, dry place away from moisture, and always keep it out of the reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Zofdan Tablets 4 mg