How do you take Folic acid; Vitamin B12?

Adults usually take 1 tablet once daily, with or without food. Swallow the tablet whole with water. If your doctor prescribed it for anaemia or pregnancy, follow their specific instructions on dosage. You can take it at any time of day, but try to take it at the same time each day so you don't forget.

What are the side effects of Folic acid; Vitamin B12?

Mild stomach upset or nausea, feeling bloated or gassy, slight change in the colour of your urine (bright yellow, which is harmless), mild diarrhoea

Who should not take Folic acid; Vitamin B12?

People who are allergic to folic acid or Vitamin B12. People with a condition called Leber's disease (a hereditary eye problem) should avoid Vitamin B12 as it can damage the optic nerve. If you have unexplained anaemia, see a doctor first before self-medicating; taking folic acid can mask the signs of serious Vitamin B12 deficiency.

OTC

Vitamin supplement (B-complex vitamins)

Folic acid; Vitamin B12

Q: What is Folic acid; Vitamin B12 used for?

Low blood (anaemia), prevention of birth defects during pregnancy, nerve problems from vitamin B12 deficiency, tiredness and weakness from low vitamins, support during pregnancy and breastfeeding

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

This is a combination vitamin supplement containing Folic acid (Vitamin B9) and Vitamin B12, which work together to help your body produce healthy red blood cells, support your nervous system, and prevent certain types of anaemia (low blood).

How it works

Serves as essential cofactors for one-carbon transfer reactions and DNA synthesis: folic acid (as tetrahydrofolate) enables nucleotide metabolism and cell division, while vitamin B12 (cobalamin) facilitates methionine synthesis and myelin formation in the nervous system. Together, they correct megaloblastic anaemia, support fetal development, and restore neurological and haematopoietic function in deficiency states.

What is it used for?

Low blood (anaemia)prevention of birth defects during pregnancynerve problems from vitamin B12 deficiencytiredness and weakness from low vitaminssupport during pregnancy and breastfeeding

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Vitamins & Supplements Anaemia Sickle Cell Disease Pregnancy & Labour

Available Over The Counter

Get this from any pharmacy or chemist: no prescription needed.

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What to watch out for

Buy only from trusted pharmacies: look for known brands like Dr. Meyer's Folic Acid + B12, MeCure's Folic Acid Tablet, or RGI Folic Acid Plus Vitamin B12 to ensure quality. Do not assume all tiredness or low blood is just vitamin deficiency; see a doctor to get a proper blood test before starting long-term use. If you are taking it for pregnancy, start early (ideally before conception) and continue as your doctor advises.

Common Side Effects

Mild stomach upset or nausea
feeling bloated or gassy
slight change in the colour of your urine (bright yellow, which is harmless)
mild diarrhoea

Serious Side Effects

Severe allergic reaction such as swelling of the face
tongue or throat with difficulty breathing: go to the hospital immediately. Numbness or tingling that gets worse instead of better: see your doctor right away.

Drug Interactions

Methotrexate (used for arthritis or cancer): folic acid can affect how this drug works, so tell your doctor if you take it. Anti-seizure drugs like phenytoin: folic acid may reduce their effectiveness. Some antibiotics like chloramphenicol may reduce the effect of Vitamin B12 on your blood.

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Pregnancy & Breastfeeding Warning

This combination is generally safe and highly recommended during pregnancy and breastfeeding. In fact, folic acid is essential to prevent birth defects, and your doctor will likely prescribe it for you.

Who Should NOT Take This

People who are allergic to folic acid or Vitamin B12. People with a condition called Leber's disease (a hereditary eye problem) should avoid Vitamin B12 as it can damage the optic nerve. If you have unexplained anaemia
see a doctor first before self-medicating; taking folic acid can mask the signs of serious Vitamin B12 deficiency.

How to Store

Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be hot, so don't leave it in your car or near a window. Keep the container tightly closed to protect from humidity, and always keep it out of reach of children.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.