Proton pump inhibitor + Antibiotics (combination ulcer treatment kit)
Last reviewed July 2026
Who is this for?
This is a combination of three medicines: esomeprazole (which reduces stomach acid), amoxicillin (an antibiotic), and clarithromycin (another antibiotic) that work together to kill the bacteria called H. pylori that causes stomach ulcers.
Inhibits gastric H+/K+-ATPase proton pump, reducing gastric acid secretion and creating an optimal environment for antibiotic activity, while amoxicillin and clarithromycin disrupt bacterial cell wall synthesis and protein synthesis respectively, eliminating H. pylori infection.
Stomach ulcer caused by H. pylori bacteria, duodenal ulcer, persistent stomach pain and burning from H. pylori infection
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue as normal. Do not take a double dose to make up for it.
Important for antibiotics
Always complete the full course even if you feel better. Stopping early can cause the infection to return and become drug-resistant.
Avoid taking this kit with blood-thinning drugs like warfarin as it can increase the risk of bleeding. Do not use with ergotamine-based migraine medicines as it can cause dangerous side effects. Avoid alcohol during the treatment as it can worsen stomach irritation and reduce the effectiveness of the medicines.
Check your specific combination
Is it safe to take Esomeprazole; with your other drugs?
This combination is not recommended during pregnancy or breastfeeding. Consult your doctor before using it if you are pregnant, planning to become pregnant, or breastfeeding.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it near windows or in your car. Keep the kit in its original pack and far away from children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.