Antiretroviral (HIV medicine)
Last reviewed July 2026
Who is this for?
This is a combination of three antiretroviral (anti-HIV) medicines: Dolutegravir, Emtricitabine, and Tenofovir Alafenamide, combined in one tablet. They work together to stop HIV from multiplying in your body, helping your immune system stay strong.
Inhibits HIV reverse transcriptase and integrase enzymes while blocking nucleotide incorporation into viral DNA, preventing viral replication and integration into the host genome. Emtricitabine and tenofovir alafenamide act as nucleoside and nucleotide reverse transcriptase inhibitors respectively, while dolutegravir functions as an integrase strand transfer inhibitor.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two tablets at once to make up for it. Try to avoid missing doses as much as possible.
Always get your ARVs from a trusted hospital, pharmacy, or government health facility. Never buy from roadside sellers or unverified sources. Do not share your HIV medication with anyone else, even if they are also HIV positive. Take your medicine every single day without stopping, as skipping doses can cause the virus to become resistant, making treatment harder.
Avoid taking this medicine at the same time as antacids, calcium, or iron supplements. Take them at least 2 hours before or 6 hours after your ARV tablet. Rifampicin (commonly used to treat TB in Nigeria) can reduce the effectiveness of Dolutegravir, so your doctor may need to adjust your dose. Alcohol can worsen liver side effects and make it harder to remember your daily dose.
Check your specific combination
Is it safe to take Dolutegravir with your other drugs?
If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor. They may continue this regimen or switch you to another one depending on your situation and stage of pregnancy.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in cars or near windows. Keep the container tightly closed to protect from humidity. Always keep out of reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.