Painkiller and anti-inflammatory (NSAID + analgesic combination)
Last reviewed July 2026
Who is this for?
This is a combination painkiller that contains two medicines: diclofenac potassium (which reduces pain, swelling, and inflammation) and paracetamol (which reduces pain and fever). Together, they work faster and stronger than either one alone.
Inhibits COX-1 and COX-2 enzymes (diclofenac potassium), reducing prostaglandin synthesis to decrease pain, fever, and inflammation; paracetamol inhibits COX-3 in the central nervous system and modulates serotonergic pathways, providing additional analgesic and antipyretic effects.
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
If you miss a dose, take it as soon as you remember, but only if it is close to the time you would normally take it. If your next dose is almost due, just skip the missed one and continue as normal. Never take two doses at once to make up for the one you missed.
Always buy from a licensed pharmacy and avoid roadside sellers or open market drugs, as fake versions of this medicine are common in Nigeria. Do not use this drug as an everyday painkiller for weeks without a doctor's supervision, as long-term use can damage your stomach, kidneys, and liver. Brands like Bioraj Paracetamol & Diclofenac Potassium Tablet, Clofenamol, and Ragezugi are available in Nigeria. Check the NAFDAC number on the pack to confirm it is genuine.
Avoid drinking alcohol while taking this medicine as it increases the risk of stomach bleeding and liver damage. Be careful if you are already taking blood pressure medicines (like lisinopril or amlodipine) because diclofenac can reduce their effect. Do not take extra paracetamol or other painkillers like ibuprofen at the same time unless your doctor says so, as this can damage your stomach, liver, or kidneys.
Check your specific combination
Is it safe to take Diclofenac with your other drugs?
This medicine is not safe during pregnancy, especially in the last three months, and should be avoided during breastfeeding. Always consult your doctor before using it if you are pregnant, planning to become pregnant, or breastfeeding.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the medicine in its original pack and always store it where children cannot reach it.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.