How do you take Dextromethorphan Hydrobromide?

Adults should take 10–20 mg every 4–6 hours, or 30 mg every 6–8 hours depending on the product. For syrups, follow the measuring cup provided, usually 2 teaspoonfuls (10 ml) every 4–6 hours. Do not take more than 120 mg in 24 hours. You can take it with or without food.

What are the side effects of Dextromethorphan Hydrobromide?

Feeling dizzy, feeling sleepy or drowsy, mild nausea or stomach upset, slight constipation

Who should not take Dextromethorphan Hydrobromide?

People allergic to dextromethorphan, children under 2 years old, anyone currently taking MAO inhibitor drugs, people with a productive (wet/chesty) cough with mucus: this drug is only for dry cough. People with liver problems should consult a doctor first.

OTC

Cough suppressant (Antitussive)

Dextromethorphan Hydrobromide

Q: What is Dextromethorphan Hydrobromide used for?

Dry cough, tickly cough, cough from cold or flu, irritating cough that keeps you up at night

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

Dextromethorphan hydrobromide is a cough suppressant that works by calming the part of your brain that triggers coughing, helping to reduce dry cough (cough without phlegm).

How it works

Binds to sigma-1 receptors and NMDA receptors in the medullary cough centre, suppressing the cough reflex and reducing airway irritation-induced coughing.

What is it used for?

Dry coughtickly coughcough from cold or fluirritating cough that keeps you up at night

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Cough & Cold Throat & Chest Infections Cough Medicines

Available Over The Counter

Get this from any pharmacy or chemist: no prescription needed.

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What to watch out for

Buy only from reputable pharmacies and avoid roadside sellers or market stalls, as fake cough syrups are common in Nigeria and can be dangerous. Do not use this medicine for more than 7 days without seeing a doctor, as a cough lasting that long may need proper investigation. Some people, especially young people, misuse this drug in high doses to get high, which is extremely dangerous and can cause serious harm or death.

Common Side Effects

Feeling dizzy
feeling sleepy or drowsy
mild nausea or stomach upset
slight constipation

Serious Side Effects

Severe allergic reaction such as swelling of the face
lips or throat and difficulty breathing: go to the hospital immediately. Confusion
hallucinations (seeing or hearing things that aren't real)
or very fast heartbeat: stop the drug and seek medical help right away.

Drug Interactions

Do not take with MAO inhibitors (some drugs used for depression), as this combination can be very dangerous and even life-threatening. Avoid alcohol while using this medicine as it can make drowsiness much worse. Be careful combining it with antihistamines like chlorpheniramine or sedatives as they increase sleepiness.

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Pregnancy & Breastfeeding Warning

Consult your doctor before using dextromethorphan if you are pregnant or breastfeeding, as it should only be used if the benefit clearly outweighs the risk.

Who Should NOT Take This

People allergic to dextromethorphan
children under 2 years old
anyone currently taking MAO inhibitor drugs
people with a productive (wet/chesty) cough with mucus: this drug is only for dry cough. People with liver problems should consult a doctor first.

How to Store

Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so don't leave it in your car or near a window. Keep the bottle tightly closed and store out of reach of children.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.