Antihistamine (anti-allergy)
Last reviewed July 2026
Who is this for?
Desloratadine is an antihistamine that blocks a chemical called histamine in your body, which is what causes allergic reactions like sneezing, itching, and runny nose. It is a newer type of antihistamine that works without making you feel as sleepy as older ones.
Binds selectively to peripheral H1 histamine receptors, blocking histamine-mediated allergic responses and preventing symptoms such as pruritus, urticaria, and rhinitis without significant central nervous system penetration.
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
If you forget a dose, take it as soon as you remember. But if it's almost time for your next dose, just skip the missed one and continue as normal. Don't take two doses at once to make up for it.
Buy only from trusted pharmacies, avoiding roadside vendors or unregistered shops, as fake drugs are common. If your allergy symptoms don't improve after a few days of use, see a doctor. Do not take more than the recommended dose thinking it will work faster: it won't, and it may cause side effects.
Alcohol can increase drowsiness when taken with desloratadine, so avoid or limit drinking. Ketoconazole (antifungal commonly used in Nigeria) and erythromycin (antibiotic) may increase the level of desloratadine in your body, so let your pharmacist know if you are taking these.
Check your specific combination
Is it safe to take Desloratadine with your other drugs?
Desloratadine should not be used during pregnancy or breastfeeding unless your doctor specifically says it is okay, as its safety has not been fully established.
Store in a cool, dry place away from direct sunlight and heat, especially important in hot Nigerian weather. Do not store in the bathroom where it's humid. Keep out of the reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.