Antipsychotic (Phenothiazine)
Last reviewed July 2026
Who is this for?
Chlorpromazine is a medicine that works by calming certain chemicals in the brain, helping to reduce agitation, disturbed thinking, and severe anxiety. It belongs to a group of drugs called phenothiazines that help balance brain activity.
Blocks dopamine (D2) receptors in the mesolimbic and mesocortical pathways of the brain, reducing psychotic symptoms, while also antagonizing alpha-adrenergic, muscarinic cholinergic, and H1 histamine receptors, contributing to its antiemetic and sedative effects.
Mental health conditions like schizophrenia (when someone hears voices or sees things that are not there), severe anxiety and agitation, uncontrollable hiccups, severe nausea and vomiting
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue your normal schedule. Never take two doses at once to make up for a missed one.
This is a strictly prescription medicine; do not buy it from roadside sellers or use someone else's prescription, as wrong dosage can be very dangerous. It makes you very drowsy so do not drive okada, keke, or any vehicle after taking it. Do not stop the medicine suddenly on your own; always let your doctor reduce the dose gradually to avoid withdrawal symptoms.
Avoid drinking alcohol while taking chlorpromazine as it can make you extremely drowsy and dangerously lower your blood pressure. Be careful if you are also taking medicines for malaria like quinine, as both can affect the heart rhythm. Antacids (like the ones used for ulcer) can reduce how well chlorpromazine works, so take them at least 2 hours apart.
Check your specific combination
Is it safe to take Chlorpromazine with your other drugs?
Chlorpromazine is not considered safe during pregnancy or breastfeeding, so do not take it without consulting your doctor first, as it can affect the baby.
Store in a cool, dry place away from direct sunlight and heat, so avoid leaving it on windowsills or in your car. Keep the medicine tightly sealed and away from moisture. Always keep it out of the reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.