Casodex 50 mg Tablets Tablet (Bicalutamide) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Bicalutamide is an anti-androgen medicine that works by blocking the effects of male hormones (like testosterone) on the body, which helps slow down or stop the growth of prostate cancer cells that depend on these hormones to grow.

What is it used for?

Advanced prostate cancer (cancer of the man's prostate gland)usually used together with other hormone treatments or surgery

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Prostate & Men's Health Cancer Treatment

How it works

Binds competitively to androgen receptors in prostate cancer cells, blocking testosterone and dihydrotestosterone (DHT) binding and inhibiting androgen-dependent tumor growth and proliferation.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Take one tablet once a day, at the same time each day. You can take it with or without food, but swallow it whole with a glass of water. Your doctor will decide whether you take the 50 mg or 150 mg strength. This medicine is usually taken alongside another hormone treatment or after prostate surgery — do not stop taking it unless your doctor tells you to. Common brands in Nigeria include Casodex, Bicatero, Bikatab, Mitide, and Prostaglob.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your normal schedule. Do not take two tablets at the same time to make up for a missed dose.

What to watch out for

This is a serious cancer medicine — only use it with a doctor's prescription and regular check-ups, including liver function tests. Do not buy from roadside sellers or unverified sources; stick to reputable pharmacies to ensure you get genuine products. Never share this medication with anyone else, even if they have similar symptoms.

Common Side Effects

Hot flushes (sudden feeling of warmth)
breast tenderness or swelling in the chest area
feeling tired or weak
stomach upset or nausea
dizziness

Serious Side Effects

Yellowing of the eyes or skin (signs of liver problems) — see a doctor immediately. Difficulty breathing
chest pain
or dark-coloured urine should also be reported to your doctor right away. Severe allergic reactions like swelling of the face or throat need emergency attention.

Drug Interactions

Bicalutamide can interact with blood thinners like warfarin, increasing the risk of bleeding — your doctor may need to adjust your warfarin dose. It may also interact with certain medications broken down by the liver, such as ketoconazole and some heart medicines. Avoid alcohol as it can put extra stress on your liver while on this medicine.

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Pregnancy & Breastfeeding Warning

Bicalutamide is strictly for men only and must never be taken by women, especially pregnant or breastfeeding women, as it can cause serious harm to an unborn baby.

Who Should NOT Take This

People who are allergic to bicalutamide or any ingredient in the tablet
women and children
men with severe liver disease
and anyone already taking terfenadine
astemizole
or cisapride should not use this medicine.

How to Store

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it on window sills or in cars. Keep it in its original pack and far away from children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Casodex 50 mg Tablets