How do you take Betamethasone; Ketoconazole?

Apply a thin layer of the cream to the affected area once or twice daily as directed by your doctor or pharmacist. Gently rub it in. Wash your hands before and after applying. Do not use it for longer than 2 weeks unless your doctor says so, as the steroid in it can damage your skin if used too long.

What are the side effects of Betamethasone; Ketoconazole?

Mild burning or stinging when you first apply it, skin dryness or peeling at the area, slight itching at the application site, thinning of the skin if used for too long

Who should not take Betamethasone; Ketoconazole?

People allergic to betamethasone, ketoconazole, or any ingredient in the cream. Do not use on open wounds, broken skin, or skin with active bacterial infections like boils. Do not apply on the face for extended periods. People with tuberculosis of the skin, chickenpox, or herpes sores should avoid it.

Prescription

Antifungal and Corticosteroid combination

Betamethasone; Ketoconazole

Q: What is Betamethasone; Ketoconazole used for?

Fungal skin infections with inflammation, ringworm (coconut), jock itch (crotch fungus), athlete's foot, stubborn rashes caused by fungal infection, itchy skin with fungal infection

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

This is a combination cream that contains two active ingredients: betamethasone (a steroid that reduces swelling, redness, and itching) and ketoconazole (an antifungal that kills fungus on the skin). Together, they treat skin infections caused by fungus while calming the irritation at the same time.

How it works

Inhibits fungal cell membrane ergosterol synthesis by blocking lanosterol 14α-demethylase (CYP51), while betamethasone binds to glucocorticoid receptors to suppress inflammatory cytokines and reduce pruritis, erythema, and associated dermatological inflammation.

What is it used for?

Fungal skin infections with inflammationringworm (coconut)jock itch (crotch fungus)athlete's footstubborn rashes caused by fungal infectionitchy skin with fungal infection

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Fungal Infections Skin Infections Eczema & Skin Rashes Fungal Skin Infections

Prescription Required

You need a doctor's prescription to buy this drug.

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What to watch out for

Do not use this cream to bleach or lighten your skin, as it is not a cosmetic product and long-term misuse causes serious skin damage that is very common in Nigeria. Buy only from reputable pharmacies and look for known brands like Chitrobact Cream, Skinfix Plus Cream, or Ketoconazole & Betamethasone Dipropionate Cream. Stop using it after the recommended period even if the rash is not fully gone: go back to your doctor instead of continuing on your own.

Common Side Effects

Mild burning or stinging when you first apply it
skin dryness or peeling at the area
slight itching at the application site
thinning of the skin if used for too long

Serious Side Effects

Stretch marks or permanent skin thinning (especially on the face or groin): stop using and see a doctor immediately. Allergic reaction such as severe swelling
rash spreading
or difficulty breathing: go to the hospital right away. Skin discolouration or dark patches that won't go away.

Drug Interactions

Avoid using other steroid creams or skin products on the same area at the same time, as this can increase side effects. Do not mix with skin-lightening or bleaching creams, as many of these already contain steroids and combining them can seriously damage your skin. If you are taking antifungal tablets like fluconazole, let your doctor know.

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Pregnancy & Breastfeeding Warning

Do not use this cream during pregnancy or while breastfeeding unless your doctor specifically prescribes it, as the steroid can be harmful to your baby.

Who Should NOT Take This

People allergic to betamethasone
ketoconazole
or any ingredient in the cream. Do not use on open wounds
broken skin
or skin with active bacterial infections like boils. Do not apply on the face for extended periods. People with tuberculosis of the skin
chickenpox
or herpes sores should avoid it.

How to Store

Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the tube tightly closed after use and keep it away from children.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.