How do you take Acetylsalicylic acid; Caffeine?

For adults, take 1 to 2 tablets or 1 sachet of powder dissolved in water, every 4 to 6 hours as needed for pain. Do not take more than 8 tablets in 24 hours. It is best to take it with food or a glass of water to protect your stomach. If using Alabukun powder, dissolve it in a small amount of water and drink immediately.

What are the side effects of Acetylsalicylic acid; Caffeine?

Stomach upset or stomach pain, feeling nauseous or wanting to vomit, heartburn or a burning feeling in your chest, slight dizziness, difficulty sleeping (because of the caffeine)

Who should not take Acetylsalicylic acid; Caffeine?

People who are allergic to aspirin or any NSAID painkiller, children under 16 years, people with stomach ulcers or a history of stomach bleeding, people with bleeding disorders like haemophilia, people with severe kidney or liver problems, people with asthma triggered by aspirin, and pregnant women especially in the third trimester.

OTC

Painkiller (analgesic) and stimulant combination

Acetylsalicylic acid; Caffeine

Q: What is Acetylsalicylic acid; Caffeine used for?

Headache, body pain, toothache, muscle pain, joint pain, menstrual pain (period pain), mild fever, back pain

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

This is a combination painkiller that contains aspirin (acetylsalicylic acid) and caffeine. Aspirin reduces pain and inflammation, while caffeine helps the aspirin work faster and better by boosting its absorption in your body.

How it works

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis to decrease pain, fever, and inflammation; caffeine competitively antagonizes adenosine receptors in the central nervous system, enhancing alertness and potentiating analgesic effects.

What is it used for?

Headachebody paintoothachemuscle painjoint painmenstrual pain (period pain)mild feverback pain

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Fever Pain Relief Headache & Migraine Arthritis & Joint Pain Menstrual Pain Toothache & Dental Muscle Cramps & Spasms Acne & Pimples

Available Over The Counter

Get this from any pharmacy or chemist: no prescription needed.

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What to watch out for

Alabukun powder is very popular in Nigeria but do not use it every day like a routine medicine, as long-term use can damage your stomach and kidneys. Do not mix Alabukun or any aspirin product with local herbs or gin as some people do, because this increases the risk of stomach bleeding. Buy only from reputable pharmacies, not from roadside vendors, to make sure the product is genuine and properly stored.

Common Side Effects

Stomach upset or stomach pain
feeling nauseous or wanting to vomit
heartburn or a burning feeling in your chest
slight dizziness
difficulty sleeping (because of the caffeine)

Serious Side Effects

Vomiting blood or seeing dark/black stool (this could mean stomach bleeding, so go to the hospital immediately)
ringing in your ears or hearing loss (sign of aspirin overdose)
severe allergic reaction with swelling of the face
lips
or difficulty breathing.

Drug Interactions

Do not take with blood-thinning drugs like warfarin, as aspirin increases the risk of serious bleeding. Avoid drinking alcohol while using this drug, as alcohol plus aspirin greatly increases the chance of stomach bleeding. Be careful if you are already taking other painkillers like ibuprofen or diclofenac, as combining them raises the risk of stomach problems.

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Pregnancy & Breastfeeding Warning

This drug is NOT safe during pregnancy, especially in the last 3 months, and should be avoided during breastfeeding. Consult your doctor before use.

Who Should NOT Take This

People who are allergic to aspirin or any NSAID painkiller
children under 16 years
people with stomach ulcers or a history of stomach bleeding
people with bleeding disorders like haemophilia
people with severe kidney or liver problems
people with asthma triggered by aspirin
and pregnant women especially in the third trimester.

How to Store

Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the powder sachets sealed until you are ready to use them. Always keep out of reach of children.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.