Libre Plus Tablet Tablet (Tizanidine; Aceclofenac) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

This is a combination drug containing tizanidine (a muscle relaxant) and aceclofenac (a painkiller that also reduces swelling). It works by relaxing tight, stiff muscles while reducing pain and inflammation at the same time.

What is it used for?

Back painneck painmuscle spasmjoint stiffnessbody pain with muscle tightnesswaist painpain from slipped discshoulder pain

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Muscle Cramps & Spasms Pain Relief

How it works

Activates alpha-2 adrenergic receptors in the spinal cord and brainstem, enhancing inhibitory neurotransmission to reduce muscle tone and spasticity. Inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis to decrease pain and inflammation in musculoskeletal conditions.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

The usual dose for adults is one tablet taken twice daily, or as your doctor prescribes. Take it with food or after eating to reduce stomach upset. Swallow the tablet whole with water — do not crush or chew it. This drug can make you feel sleepy, so avoid driving or operating machines after taking it.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two tablets at once to make up for the missed dose.

What to watch out for

Only use this drug as prescribed by your doctor — do not buy it from roadside sellers or use someone else's prescription. Because it causes drowsiness, avoid taking it before driving, especially on Lagos or city roads. Do not use it for longer than your doctor recommends, as long-term use can damage your stomach, liver, or kidneys.

Common Side Effects

Feeling sleepy or drowsy
dizziness
dry mouth
stomach discomfort or mild belly pain
feeling weak or tired

Serious Side Effects

Dark or bloody stool (which could mean stomach bleeding) — go to the hospital immediately. Yellowing of the eyes or skin (signs of liver problem) — stop the drug and see a doctor right away. Severe skin rash
swelling of the face or difficulty breathing (allergic reaction) — seek emergency help.

Drug Interactions

Avoid drinking alcohol while taking this drug — it increases drowsiness and raises your risk of stomach bleeding. Do not combine with other painkillers like ibuprofen or diclofenac as this can damage your stomach and kidneys. If you are taking blood pressure drugs, let your doctor know because tizanidine can cause your blood pressure to drop too low.

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Pregnancy & Breastfeeding Warning

This drug is not safe during pregnancy, especially in the last three months, and should be avoided during breastfeeding — consult your doctor before use.

Who Should NOT Take This

People with stomach ulcers or a history of stomach bleeding
people with serious liver or kidney problems
people allergic to tizanidine
aceclofenac
or other painkillers like aspirin or ibuprofen
and people with heart failure should not take this drug.

How to Store

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so do not leave it in your car or near a window. Keep it in its original pack and far away from children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Libre Plus Tablet