Sacuvan 24 mg/26 mg Tablets Tablet (Sacubitril; Valsartan) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Sacubitril/Valsartan is a combination heart medicine that works in two ways — one part (sacubitril) helps your body remove extra fluid and relax blood vessels, while the other part (valsartan) lowers blood pressure and reduces strain on the heart.

What is it used for?

Heart failure (weak heart that cannot pump blood well)high blood pressureswollen legs and ankles from heart problems

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High Blood Pressure Heart Conditions Heart Failure

How it works

Blocks angiotensin II type-1 (AT1) receptors to reduce vasoconstriction and aldosterone release, while simultaneously inhibiting neprilysin to prevent degradation of natriuretic peptides, collectively reducing cardiac afterload, promoting vasodilation, and improving heart function.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Adults usually start with one low-dose tablet (e.g. Sacuvan 24/26 mg or Uperio 50 mg) taken twice daily — morning and evening. Your doctor will gradually increase the dose every 2-4 weeks depending on how your body responds. You can take it with or without food, but try to take it at the same times each day.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take two tablets at once to make up for a missed dose.

What to watch out for

Only buy this medicine from licensed pharmacies — do not purchase from roadside vendors or open markets as fake heart drugs are dangerous and can kill. Do not stop taking it on your own even if you feel better, as heart failure needs continuous management. Always attend your follow-up appointments so your doctor can check your kidney function and potassium levels.

Common Side Effects

Dizziness or lightheadedness (especially when standing up quickly)
low blood pressure
cough
tiredness
and high potassium levels in the blood which may cause muscle weakness

Serious Side Effects

Swelling of the face
lips
tongue or throat making it hard to breathe (this is an emergency — go to hospital immediately)
severe dizziness or fainting
and signs of kidney problems like very little urine or swelling in your legs.

Drug Interactions

Do not take with ACE inhibitors like lisinopril, enalapril, or ramipril — you must stop these for at least 36 hours before starting this medicine. Avoid potassium supplements or salt substitutes that contain potassium, as this drug already raises potassium levels. Avoid drinking alcohol as it can make your blood pressure drop dangerously low.

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Pregnancy & Breastfeeding Warning

This medicine is NOT safe during pregnancy — it can cause serious harm or death to your unborn baby, especially in the second and third trimesters. If you are pregnant, planning to become pregnant, or breastfeeding, do not take this drug and talk to your doctor immediately.

Who Should NOT Take This

People allergic to sacubitril
valsartan
or any ingredient in the tablet; anyone who has had swelling of the face or throat (angioedema) from ACE inhibitors; people currently taking ACE inhibitors like enalapril or lisinopril; people with severe liver disease; diabetics taking aliskiren; and pregnant women.

How to Store

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep it in its original pack and far from the reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Sacuvan 24 mg/26 mg Tablets