Question 1

What is Sacubitril; Valsartan used for?

Accepted Answer

Heart failure (weak heart that cannot pump blood well), high blood pressure, swollen legs and ankles from heart problems

Question 2

How do you take Sacubitril; Valsartan?

Accepted Answer

Adults usually start with one low-dose tablet (e.g. Sacuvan 24/26 mg or Uperio 50 mg) taken twice daily — morning and evening. Your doctor will gradually increase the dose every 2-4 weeks depending on how your body responds. You can take it with or without food, but try to take it at the same times each day.

Question 3

What are the side effects of Sacubitril; Valsartan?

Accepted Answer

Dizziness or lightheadedness (especially when standing up quickly), low blood pressure, cough, tiredness, and high potassium levels in the blood which may cause muscle weakness

Question 4

Who should not take Sacubitril; Valsartan?

Accepted Answer

People allergic to sacubitril, valsartan, or any ingredient in the tablet; anyone who has had swelling of the face or throat (angioedema) from ACE inhibitors; people currently taking ACE inhibitors like enalapril or lisinopril; people with severe liver disease; diabetics taking aliskiren; and pregnant women.

Question 5

Is Sacubitril; Valsartan safe during pregnancy?

Accepted Answer

This medicine is NOT safe during pregnancy — it can cause serious harm or death to your unborn baby, especially in the second and third trimesters. If you are pregnant, planning to become pregnant, or breastfeeding, do not take this drug and talk to your doctor immediately.

Sacubitril; Valsartan

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