Who is this for?
What is this drug?
Saccharomyces boulardii is a beneficial yeast (a type of probiotic) that helps restore the natural balance of good organisms in your gut, which helps your digestive system work properly and fight off harmful bacteria.
What is it used for?
Diarrhoea (running stomach)antibiotic-related diarrhoeatraveller's diarrhoeastomach upset from infectionsprevention of recurring diarrhoea caused by a germ called Clostridium difficile
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How it works
Inhibits pathogenic bacterial adhesion to intestinal epithelium through competitive colonisation and production of antimicrobial metabolites, while simultaneously stimulating intestinal IgA secretion and strengthening the intestinal barrier function to prevent toxin translocation and restore normal microbiota balance.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
How to take this drug
Adults usually take 250 mg to 500 mg once or twice daily. For sachets or powder, dissolve in a small glass of water or mix with food — avoid very hot liquids as heat kills the yeast. You can take it with or without food. Continue taking it for the duration your pharmacist or doctor recommends, usually throughout your episode of diarrhoea or antibiotic course.
What if I Miss a Dose?
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue as normal. Do not double up to make up for the missed dose.
What to watch out for
Buy only from reputable pharmacies — brands like Bioflor are well known in Nigeria, so avoid unbranded or repackaged versions from roadside sellers. Do not mix the powder or sachet with very hot drinks or food, as high temperature destroys the live yeast. If your diarrhoea does not improve within 2-3 days or gets worse, see a doctor — running stomach can cause dangerous dehydration, especially in children.
Common Side Effects
- Mild bloating or gas
- mild stomach discomfort
- constipation
- feeling thirsty
Serious Side Effects
- Fungal infection in the blood (signs include high fever
- chills
- and feeling very unwell) — this is very rare but serious
- especially in people with weak immune systems. Severe allergic reaction such as swelling of the face
- difficulty breathing
- or widespread rash — go to the hospital immediately.
Drug Interactions
Do not take with antifungal medicines like fluconazole or ketoconazole, as these will kill the beneficial yeast and make it useless. If you are on antibiotics, take Saccharomyces boulardii at least 2 hours apart from your antibiotic dose. Alcohol is not known to interact directly, but it can worsen diarrhoea, so it is best avoided while you are treating a stomach problem.
Check your specific combination
Is it safe to take Saccharomyces with your other drugs?
Pregnancy & Breastfeeding Warning
Saccharomyces boulardii is generally considered safe, but pregnant and breastfeeding women should consult their doctor or pharmacist before using it.
Who Should NOT Take This
- People who are allergic to yeast or any ingredient in the product
- patients with central venous catheters (tubes placed in large veins for hospital treatment)
- and people with severely weakened immune systems such as those on chemotherapy or with advanced HIV should not take this drug without medical supervision.
How to Store
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing it near windows or in your car. Keep it below 25°C if possible. Always keep it out of the reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Brand Names
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Brand Packaging Images
Genuine packaging for Bioflor 250 mg Sachet
Adult
mrdokita.com.ng
mrdokita.com.ngImage not available
Bioflor 250 mg Sachet — Reference Image
NAFDAC Number
A4-101188
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Authenticity Checklist
If your packaging looks significantly different from this image, do not use the drug and report it below.