Probiotic (beneficial yeast supplement)
Last reviewed July 2026
Who is this for?
Saccharomyces boulardii is a beneficial yeast (a type of probiotic) that helps restore the natural balance of good organisms in your gut, which helps your digestive system work properly and fight off harmful bacteria.
Inhibits pathogenic bacterial adhesion to intestinal epithelium through competitive colonisation and production of antimicrobial metabolites, while simultaneously stimulating intestinal IgA secretion and strengthening the intestinal barrier function to prevent toxin translocation and restore normal microbiota balance.
Diarrhoea (running stomach), antibiotic-related diarrhoea, traveller's diarrhoea, stomach upset from infections, prevention of recurring diarrhoea caused by a germ called Clostridium difficile
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue as normal. Do not double up to make up for the missed dose.
Buy only from reputable pharmacies. Brands like Bioflor are well known in Nigeria, so avoid unbranded or repackaged versions from roadside sellers. Do not mix the powder or sachet with very hot drinks or food, as high temperature destroys the live yeast. If your diarrhoea does not improve within 2-3 days or gets worse, see a doctor, as running stomach can cause dangerous dehydration, especially in children.
Do not take with antifungal medicines like fluconazole or ketoconazole, as these will kill the beneficial yeast and make it useless. If you are on antibiotics, take Saccharomyces boulardii at least 2 hours apart from your antibiotic dose. Alcohol is not known to interact directly, but it can worsen diarrhoea, so it is best avoided while you are treating a stomach problem.
Check your specific combination
Is it safe to take Saccharomyces with your other drugs?
Saccharomyces boulardii is generally considered safe, but pregnant and breastfeeding women should consult their doctor or pharmacist before using it.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid storing it near windows or in your car. Keep it below 25°C if possible. Always keep it out of the reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
Tap a brand for packaging, NAFDAC details and authenticity check
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.