Regalgan Tablets Tablet (Pitofenone Hydrochloride; Fenpiverinium Bromide; Acetaminophen) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

This is a combination drug containing three active ingredients — pitofenone (a muscle relaxant that eases muscle spasms in your stomach and intestines), fenpiverinium (which helps reduce cramping by blocking certain nerve signals), and acetaminophen (a painkiller and fever reducer also known as paracetamol). Together, they work to relieve pain and spasms in your belly and internal organs.

What is it used for?

Stomach crampsabdominal painmenstrual pain (period pain)pain from kidney stonespain from gallstonescolicspasms of the urinary tractbelly spasms

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Pain Relief

How it works

Blocks smooth muscle contraction by inhibiting phosphodiesterase and calcium influx (pitofenone and fenpiverinium), while acetaminophen inhibits prostaglandin synthesis via COX inhibition, together providing antispasmodic and analgesic effects for visceral pain relief.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Adults typically take 1 to 2 tablets up to 3 times a day, preferably after food to reduce stomach upset. Swallow the tablet whole with a glass of water. Do not take more than 6 tablets in 24 hours. This medicine is commonly sold as Regalgan Tablets in Nigeria.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue as normal. Do not take a double dose to make up for the one you missed.

What to watch out for

Do not combine Regalgan with other paracetamol products — many Nigerian drugs contain paracetamol, so check the label to avoid overdose. Buy only from licensed pharmacies, not from roadside vendors or open markets where storage conditions are poor. If your pain does not improve after a few days, see a doctor rather than increasing the dose on your own.

Common Side Effects

Dry mouth
feeling dizzy or lightheaded
mild nausea or stomach discomfort
blurred vision
feeling sleepy

Serious Side Effects

Severe allergic reaction such as swelling of the face
lips
or throat and difficulty breathing — go to the hospital immediately. Yellowing of the eyes or skin (jaundice)
which may indicate liver damage from the paracetamol component. Inability to urinate or very fast heartbeat — seek medical help right away.

Drug Interactions

Avoid drinking alcohol while taking this medicine, as it increases the risk of liver damage from the paracetamol and can worsen dizziness. Do not combine with other paracetamol-containing drugs (like Panadol or other cold remedies) to avoid overdose. Be careful if you are already taking sedatives, sleeping pills, or other drugs that cause drowsiness.

Check your specific combination

Is it safe to take Pitofenone with your other drugs?

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Pregnancy & Breastfeeding Warning

Do not take this drug during pregnancy or while breastfeeding unless your doctor specifically tells you it is safe — consult your doctor first.

Who Should NOT Take This

People allergic to any of the three ingredients
people with severe liver or kidney problems
people with glaucoma (high eye pressure)
people with enlarged prostate or difficulty urinating
people with certain bowel obstructions
and children under 12 years without a doctor's guidance.

How to Store

Store in a cool, dry place away from direct sunlight and heat — this is especially important in Nigeria's hot climate. Keep the tablets in their original packaging and always store out of reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Regalgan Tablets