NSAID (Non-Steroidal Anti-Inflammatory Drug): Eye preparation
Last reviewed July 2026
Who is this for?
Nepafenac is an eye drop that reduces pain and swelling in the eye. It belongs to a group of medicines called NSAIDs (non-steroidal anti-inflammatory drugs) and works by blocking chemicals in the body that cause inflammation.
Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin production in ocular tissues and thereby suppressing post-operative pain and inflammation. The prodrug is converted to its active amide form in the eye, allowing sustained anti-inflammatory activity at the surgical site.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue your regular schedule. Do not use double drops to make up for the missed dose.
Only buy from a registered pharmacy, with brands like Nevanac or Tevanac coming in properly sealed packaging. Do not share your eye drops with anyone else, as this can spread infection. If your vision gets worse or the eye pain increases after using the drops, stop and see your eye doctor immediately.
If you are using other eye drops, wait at least 5 minutes between each drop to avoid diluting the medicine. Nepafenac may interact with other NSAID painkillers like ibuprofen or diclofenac, increasing the risk of bleeding or eye problems. If you use steroid eye drops (like prednisolone eye drops), tell your doctor as using them together may increase the risk of eye complications.
Check your specific combination
Is it safe to take Nepafenac with your other drugs?
Nepafenac eye drops should be avoided during pregnancy, especially in the last three months, and during breastfeeding unless your doctor says it is absolutely necessary.
Store at room temperature, away from direct sunlight and heat, as this is especially important in hot Nigerian weather. Keep the bottle tightly closed when not in use. Store away from children and do not use the drops after the expiry date or more than 4 weeks after opening the bottle.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.