Eproxen Tablet (Naproxen; Esomeprazole) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

This is a combination drug containing naproxen (a painkiller and anti-inflammatory medicine) and esomeprazole (a stomach-protecting medicine that reduces acid). The esomeprazole is added to help protect your stomach from the irritation and ulcers that naproxen can cause.

What is it used for?

Arthritis (joint pain and swelling)back painbody painstiffness and swelling in jointsespecially for people who are at risk of getting stomach ulcers from regular painkillers

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Pain Relief

How it works

Inhibits COX-1 and COX-2 enzymes to reduce prostaglandin-mediated pain and inflammation, while esomeprazole blocks H+/K+-ATPase proton pumps in gastric parietal cells to suppress gastric acid secretion and protect against NSAID-induced ulceration.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

The usual dose is one tablet twice daily — one in the morning and one in the evening. Swallow the tablet whole with water; do not crush, chew, or break it. It is best taken at least 30 minutes before a meal.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two tablets at once to make up for the missed dose.

What to watch out for

Only buy from licensed pharmacies — this is a prescription medicine, so avoid buying from roadside sellers or open markets where you cannot be sure of the quality. Do not use this drug for everyday body pain or headache — it is meant for specific conditions and long-term use should be monitored by a doctor. If you notice dark-coloured stool or stomach pain that gets worse, stop the drug and see your doctor immediately.

Common Side Effects

Stomach upset or mild belly discomfort
heartburn or gas
headache
dizziness
mild diarrhea or constipation

Serious Side Effects

Black or bloody stool
or vomiting blood — this could mean bleeding in your stomach. Chest pain
sudden difficulty breathing
or swelling of the face and throat — this could be a severe allergic reaction. Sudden severe stomach pain that does not go away — this may mean a stomach ulcer has developed.

Drug Interactions

Avoid taking this with other painkillers like ibuprofen or diclofenac as this increases the risk of stomach bleeding. If you are taking blood-thinning medicines like warfarin or aspirin, talk to your doctor first as the combination can cause dangerous bleeding. Avoid alcohol while using this drug as it greatly increases your risk of stomach problems.

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Pregnancy & Breastfeeding Warning

This medicine is not safe during pregnancy, especially in the last three months, and should be avoided during breastfeeding — always consult your doctor before use.

Who Should NOT Take This

People allergic to naproxen
aspirin
ibuprofen
or esomeprazole should not take this drug. People with active stomach ulcers
kidney problems
or a history of bleeding in the stomach should avoid it. It should also not be used by anyone about to have or who just had heart bypass surgery
or by people with severe heart failure.

How to Store

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep it in its original container and far away from children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Eproxen