Prostaglandin analogue (stomach protector and uterine stimulant)
Brand of Misoprostol
Last reviewed May 2026
NAFDAC registration currently inactive
This product's NAFDAC registration is not currently active. It may still be available in pharmacies, but you should verify its status with your pharmacist before use.
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Misoprostol is a synthetic prostaglandin — a hormone-like substance that protects the stomach lining from acid damage and also causes the womb (uterus) to contract. It works by reducing stomach acid production and strengthening the stomach's natural protective barrier.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For stomach ulcer prevention: Take one 200 mcg tablet four times a day with food, or one 400 mcg dose twice daily with food. Always take it with meals to reduce diarrhoea. Swallow the tablet whole — do not crush or chew. Your doctor will tell you the exact dose depending on what it is being used for.
If you miss a dose, take it as soon as you remember — but only if it is close to the time you would normally take it. If it is almost time for your next dose, skip the missed one and continue as normal. Do not take two tablets at once to make up for a missed dose.
This is a prescription-only medicine — do not buy from roadside vendors or market sellers, as fake or expired versions are dangerous and common. Women of childbearing age must have a negative pregnancy test before starting misoprostol for ulcer treatment. Never share this drug with others, especially pregnant women, as it can cause life-threatening complications.
Antacids containing magnesium (like magnesium trisilicate) can make diarrhoea worse when taken with misoprostol — use aluminium-based antacids instead. NSAIDs like ibuprofen and diclofenac — misoprostol is often used alongside them but your doctor must guide the combination. Alcohol can increase stomach irritation and worsen side effects, so avoid it.
Check your specific combination
Is it safe to take Misoprostol with your other drugs?
Misoprostol is NOT safe during pregnancy — it can cause miscarriage, premature birth, or serious birth defects, and should never be taken by pregnant women or women who might be pregnant unless specifically directed by a doctor in a hospital setting.
Store in a cool, dry place below 25°C — away from direct sunlight and humidity. In hot Nigerian weather, keep it in a cupboard or drawer, not near windows or in the kitchen. Keep out of reach of children and away from anyone who might take it by mistake, especially pregnant women.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Eprostol 25 Tablet
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NAFDAC Number
A4-5420
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