Topical analgesic (pain-relieving rub)
Last reviewed June 2026
Who is this for?
This is a topical pain-relieving cream or ointment that combines methyl salicylate (a warming pain reliever related to aspirin) and menthol (a cooling agent from mint) to reduce pain and stiffness in muscles and joints by creating a warming-then-cooling sensation that distracts from pain and improves blood flow to the area.
Activates TRPM8 and TRPA1 cold-sensitive receptors (menthol) and inhibits COX enzymes (methyl salicylate), producing local anesthesia, counter-irritation, and reduced inflammatory mediator production at the site of application. This dual mechanism provides rapid pain relief through sensory gate closure and decreased prostaglandin-mediated inflammation in musculoskeletal tissues.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
Apply a thin layer of the ointment to the painful area and gently rub it in. Use it 2 to 3 times a day or as needed. Do not bandage tightly over it, and always wash your hands after applying unless you are treating your hands.
Since this is applied only when you feel pain, there is no strict schedule. Simply apply it when you remember or when you next feel pain. Do not apply extra to make up for a missed application.
Buy from trusted pharmacies — products like Neurogesic Greaseless Ointment should be purchased from reputable stores, not roadside sellers, to avoid fake products. Do not apply near your eyes, nose, mouth, or private parts. If the pain does not improve after 7 days of use, see a doctor rather than continuing to self-treat.
Do not use this ointment together with a heating pad or hot water bottle as it can cause serious burns. Avoid using it alongside other topical pain creams like diclofenac gel to prevent skin irritation. If you are already taking blood-thinning medicines like warfarin or aspirin by mouth, consult your doctor before using, as methyl salicylate can increase bleeding risk.
Check your specific combination
Is it safe to take Methyl with your other drugs?
Pregnant and breastfeeding women should consult their doctor before using this product, especially during the last three months of pregnancy, as methyl salicylate is related to aspirin and may affect the baby.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the cap tightly closed and store out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.