Antidiabetic (Biguanide + DPP-4 Inhibitor combination)
Brand of Metformin Hydrochloride; Vildagliptin
Last reviewed June 2026
Who is this for?
This is a combination tablet containing two diabetes medicines — Metformin and Vildagliptin — that work together to control blood sugar levels. Metformin helps your body use insulin better and reduces sugar made by the liver, while Vildagliptin helps your body produce more insulin after meals and reduces excess sugar production.
Inhibits hepatic gluconeogenesis and increases peripheral glucose utilization via mitochondrial complex I suppression (metformin), while blocking dipeptidyl peptidase-4 (DPP-4) to prolong incretin hormone activity and enhance postprandial insulin secretion (vildagliptin).
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
Take one tablet twice daily with or just after food to reduce stomach upset. Your doctor will decide the right strength for you based on your current blood sugar level. Swallow the tablet whole with water — do not crush or chew it. Try to take it at the same times each day, for example morning and evening meals.
If you miss a dose, take it as soon as you remember — but only if it is close to a mealtime. If it is almost time for your next dose, skip the missed one and continue your normal schedule. Never take a double dose to make up for the one you missed.
Always buy from a licensed pharmacy — brands like Galvusmet, Gliptus Plus, or Vildamet should come in proper sealed packaging; avoid roadside sellers or unverified sources. Do not stop taking this medicine on your own even if you feel fine — sugar disease needs continuous management. Learn to recognize signs of low blood sugar (shakiness, sweating, confusion) and carry sugar or a sweet drink with you in case it happens.
Alcohol — drinking alcohol while on this medicine can dangerously lower your blood sugar and increase the risk of lactic acidosis, so avoid or greatly limit alcohol. If you are taking other diabetes medicines like glibenclamide or insulin, the combination may cause your blood sugar to drop too low. Certain kidney medicines or contrast dyes used for scans can interact badly — always tell your doctor about all your medications.
Check your specific combination
Is it safe to take Metformin with your other drugs?
This medicine is not recommended during pregnancy or breastfeeding — if you are pregnant, planning to become pregnant, or nursing, consult your doctor immediately for a safer alternative.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep in the original pack and always keep away from children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Xavat 50 mg/1000 mg Tablets
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NAFDAC Number
A4-100718
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