Lamivudine & Tenofovir Disoproxil Fumarate Tablets 300/300 mg Film coated tablet (Lamivudine; Tenofovir Disoproxil Fumarate) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

This is a combination of two antiviral medicines (Lamivudine and Tenofovir Disoproxil Fumarate) that work together to stop the HIV virus from multiplying in your body, helping your immune system stay strong.

What is it used for?

HIV infectionprevention of HIV (PrEP in some cases)Hepatitis B virus infection

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How it works

Inhibits HIV and HBV reverse transcriptase by competing with natural nucleotides/nucleotides for incorporation into viral DNA, causing chain termination and preventing viral replication. Both agents are nucleoside/nucleotide analogs that require intracellular phosphorylation to achieve their active forms.

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Take 1 tablet once a day, with or without food. Try to take it at the same time every day so you don't forget. Swallow the tablet whole with water. Do not stop taking this drug without your doctor's approval, even if you feel fine.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Never take two tablets at once to make up for the missed dose.

What to watch out for

Always buy this medicine from a licensed pharmacy — do not buy HIV drugs from roadside sellers or unverified online stores, as fake drugs are common and very dangerous. Never share your HIV medication with anyone else, even if they have the same condition. Take this medicine every single day without skipping — missing doses can cause the virus to become resistant and make the drug stop working for you.

Common Side Effects

Headache
feeling tired or weak
stomach upset or nausea
diarrhea
dizziness

Serious Side Effects

Severe stomach pain with nausea and vomiting which could be a sign of a dangerous condition called lactic acidosis — go to the hospital immediately. Kidney problems such as passing very little urine
swelling in your legs
or unusual tiredness. If your skin or eyes turn yellow (jaundice)
especially after stopping the drug
seek urgent medical help.

Drug Interactions

Avoid taking this medicine with other drugs that can harm your kidneys, such as some painkillers like ibuprofen or diclofenac taken regularly. Do not combine with other medicines containing Tenofovir or Lamivudine to avoid double-dosing. Inform your doctor if you are taking any traditional or herbal medicines, as these may interfere with how the drug works.

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Pregnancy & Breastfeeding Warning

This drug may be used during pregnancy and breastfeeding under a doctor's supervision — do not start or stop it on your own if you are pregnant or breastfeeding, always consult your doctor first.

Who Should NOT Take This

People who are allergic to Lamivudine or Tenofovir should not take this drug. People with serious kidney problems should avoid it or use it only under close medical supervision. If you have liver disease
especially Hepatitis B
do not stop this medicine suddenly without your doctor's advice as it can cause a dangerous flare-up.

How to Store

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near a window. Keep the container tightly closed and always keep it out of the reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Lamivudine & Tenofovir Disoproxil Fumarate Tablets 300/300 mg