Who is this for?
Ketoconazole is an antifungal medicine that works by killing fungi and yeast that cause infections on your skin or inside your body. It stops the fungus from growing by damaging its protective outer layer.
Inhibits fungal cytochrome P450 14α-demethylase (lanosterol 14α-demethylase), disrupting ergosterol synthesis in the fungal cell membrane and causing membrane dysfunction and cell death.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
For tablets: Take one 200mg tablet once daily with food — eating helps your body absorb it better. For serious infections, your doctor may increase to two tablets (400mg) daily. For cream: Apply a thin layer to the affected area once or twice daily and rub in gently. Treatment usually lasts 2 to 6 weeks depending on the infection — do not stop early even if it looks better.
If you miss a dose, take it as soon as you remember. But if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not take two doses at once to make up for the one you missed.
Buy only from reputable pharmacies — many fake antifungal creams are sold by roadside vendors in Nigeria and may not contain the right amount of medicine. Complete the full course of treatment even if the infection looks healed, as stopping early can cause the fungus to come back stronger. If you are taking the tablets, your doctor should check your liver function regularly — report any unusual tiredness, loss of appetite, or yellowing of eyes immediately.
Do not take ketoconazole with alcohol — it increases the risk of liver damage and can make you feel very sick. Avoid taking it with antacids or ulcer drugs like omeprazole, as they reduce how well ketoconazole works — take ketoconazole at least 2 hours before these drugs. It can dangerously interact with some heart and cholesterol medicines, so tell your doctor or pharmacist about all other drugs you are taking.
Check your specific combination
Is it safe to take Ketoconazole with your other drugs?
Ketoconazole tablets are NOT safe during pregnancy or breastfeeding as they can harm the baby — the cream may be used with caution, but always consult your doctor first.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid storing near windows or in cars. Keep the cream tube tightly closed after use. Always keep out of reach of children.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.
Genuine packaging for Ketoconazole Cream 20 mg
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NAFDAC Number
A4-101035
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