Diamicron MR 60 mg Tablets

Who is this for?

Gliclazide is a diabetes medicine that works by telling your pancreas to produce more insulin, which helps lower the sugar level in your blood.

Binds to ATP-sensitive potassium channels on pancreatic beta cells, closing these channels and depolarizing the cell membrane to trigger insulin secretion. This increases circulating insulin levels, enhancing glucose uptake by peripheral tissues and reducing blood glucose concentration.

Is Gliclazide safe to take with another drug?

For regular tablets (like Diabend 80 or Glycinorm-80): Start with one 80mg tablet daily, taken with breakfast. Your doctor may increase this up to 2-4 tablets daily (160-320mg), usually split into two doses — morning and evening with meals. For MR (modified-release) tablets like Diamicron MR 60mg or Diabend MR 30: Take one tablet once daily with breakfast. Swallow whole — do not crush or chew MR tablets. Always take with food to reduce the risk of low blood sugar.

If you miss a dose, take it as soon as you remember — but only if it is close to your next meal. If it is almost time for your next dose, skip the missed one. Never take a double dose to make up for it.

• Low blood sugar (you may feel shaky
• dizzy
• sweaty
• or very hungry)
• stomach pain or upset
• nausea
• headache
• mild skin rash

Alcohol can dangerously lower your blood sugar when combined with gliclazide — avoid or limit drinking. NSAIDs like ibuprofen (common painkillers Nigerians take for body pain) can increase the effect of gliclazide and cause low blood sugar. If you are taking other diabetes drugs like metformin or insulin, your doctor needs to adjust your doses carefully to avoid dangerously low sugar levels.

Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can be very hot, so avoid leaving it in your car or near windows. Keep in the original pack and far from the reach of children.