Miconazole Nitrate, Fluocinolone Acetonide & Gentamicin Sulphate Cream

Who is this for?

This is a combination cream that contains three active ingredients: fluocinolone (a steroid that reduces swelling, redness, and itching), miconazole (an antifungal that kills fungal infections), and gentamicin (an antibiotic that kills bacteria). Together, they treat skin infections that involve inflammation, fungus, and bacteria at the same time.

Inhibits fungal ergosterol synthesis via lanosterol 14α-demethylase (miconazole), suppresses bacterial protein synthesis by binding to the 30S ribosomal subunit (gentamicin), and activates glucocorticoid receptors to reduce inflammatory cytokines and immune cell infiltration (fluocinolone).

Is Fluocinolone; safe to take with another drug?

Apply a thin layer of the cream to the affected area of skin 2 to 3 times a day. Gently rub it in. Wash your hands before and after applying unless your hands are the area being treated. Use it for the number of days your doctor or pharmacist tells you — usually 2 to 4 weeks.

If you forget to apply the cream, apply it as soon as you remember. If it is almost time for your next application, skip the missed one and continue as normal. Do not apply extra cream to make up for the missed dose.

• Mild burning or stinging feeling when you first apply it
• slight skin dryness or peeling
• itching at the application site
• skin thinning if used for too long
• slight lightening of the skin where applied

Avoid using other steroid creams or ointments on the same area at the same time as this can increase side effects. Do not apply other skin products like bleaching creams or strong soaps on the treated area. If you are using warfarin (blood thinner), mention this cream to your doctor as miconazole may interact with it.

Store at room temperature, away from direct sunlight and heat. In hot Nigerian weather, keep it in a cool, dry place — not inside a car or near a window. Keep the tube tightly closed and out of reach of children.