Cough and cold combination medicine (antihistamine, decongestant, expectorant)
Last reviewed June 2026
Who is this for?
This is a combination cough and cold medicine that works in several ways — ephedrine opens up blocked airways, chlorphenamine stops allergic reactions like runny nose and sneezing, ammonium chloride helps loosen thick catarrh so you can cough it out, sodium citrate soothes irritated throat, and menthol gives a cooling feeling that eases breathing.
Activates α-adrenergic receptors causing nasal vasoconstriction to relieve congestion; blocks H1 histamine receptors to reduce sneezing and rhinorrhoea; increases mucus fluidity via expectorant action; and provides local analgesic and cooling effects via menthol, while ammonium chloride and sodium citrate help mobilize airway secretions.
Available Over The Counter
Get this from any pharmacy or chemist — no prescription needed.
Explore this drug
For adults, take 10ml (two medicine spoons) three to four times a day. You can take it with or without food. Shake the bottle well before use. Use the measuring cup or spoon that comes with the bottle — don't just guess.
If you miss a dose, take it as soon as you remember. But if it's almost time for the next dose, just skip the missed one and continue as normal. Don't double the dose to catch up.
This medicine can make you very drowsy, so do not drive or operate machines after taking it. Buy only from a registered pharmacy — not from roadside sellers or bus hawkers, as fake cough syrups are common in Nigeria. Do not use this medicine for more than 7 days without seeing a doctor.
Avoid drinking alcohol while taking this medicine as it will make the drowsiness much worse. Do not take it together with other cough and cold medicines as they may contain similar ingredients, leading to overdose. If you are taking medicine for high blood pressure or depression, talk to your pharmacist first as this drug can interfere with them.
Check your specific combination
Is it safe to take Ephedrine; with your other drugs?
This medicine is not recommended during pregnancy or breastfeeding — consult your doctor before using it.
Store in a cool, dry place away from direct sunlight and heat — Nigerian weather can spoil medicines quickly. Keep the bottle tightly closed after use. Always keep it far away from children's reach.
For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under — especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.