Antiviral (Direct-Acting Antiviral - NS5A Inhibitor)
Last reviewed July 2026
Who is this for?
Daclatasvir is an antiviral medicine that fights the hepatitis C virus by blocking a protein the virus needs to multiply in your body. It is usually taken together with another antiviral drug called sofosbuvir to clear the virus from your system.
Inhibits hepatitis C virus (HCV) NS5A protein, blocking viral replication and assembly. This prevents the formation of infectious viral particles and reduces viral load in chronically infected patients.
Chronic hepatitis C infection (long-term liver infection caused by the hepatitis C virus)
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you miss a dose and it is less than 20 hours since you were supposed to take it, take it as soon as you remember. If it is more than 20 hours late, skip that dose and take the next one at your normal time. Do not take two tablets at once to make up for the missed dose.
Always complete the full course of treatment even if you start feeling fine, as stopping early can allow the hepatitis C virus to come back and become harder to treat. Only buy Mydekla or any daclatasvir brand from licensed pharmacies, not from roadside sellers or unverified online shops, as fake hepatitis C drugs are common. Do not share this medicine with anyone else, even if they also have hepatitis C, as treatment must be prescribed individually by a doctor.
Do not take daclatasvir with certain TB drugs like rifampicin or certain HIV drugs like efavirenz, as they can reduce its effectiveness; always tell your doctor about all medicines you are taking. Avoid herbal remedies like St. John's wort as they can also make daclatasvir less effective. Amiodarone (a heart drug) combined with daclatasvir and sofosbuvir can cause dangerously slow heartbeat, so inform your doctor if you use any heart medication.
Check your specific combination
Is it safe to take Daclatasvir with your other drugs?
Daclatasvir is not recommended during pregnancy or breastfeeding unless your doctor decides the benefit outweighs the risk. Consult your doctor before using it if you are pregnant, planning to become pregnant, or breastfeeding.
Store at room temperature, away from direct sunlight and heat, which is important in hot Nigerian weather. Keep the tablets in their original container, away from moisture and humidity. Always store out of reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.