Very potent topical corticosteroid with skin-nourishing vitamin
Last reviewed July 2026
Who is this for?
Clobetasol Propionate + Vitamin E is a combination cream or lotion that pairs a very strong steroid (clobetasol) with Vitamin E. The steroid works by reducing swelling, redness, and itching on your skin, while Vitamin E helps nourish and moisturize the skin to support healing.
Binds to glucocorticoid receptors in the cytoplasm, translocating to the nucleus to suppress pro-inflammatory gene expression and reduce infiltration of immune cells, while vitamin E provides antioxidant protection and enhances skin barrier function and healing.
Prescription Required
You need a doctor's prescription to buy this drug.
Explore this drug
If you forget to apply it, use it as soon as you remember. But if it is almost time for your next application, just skip the missed one and continue your normal schedule. Do not apply double the amount to make up for the missed dose.
This is a very strong steroid cream, so do not use it as a general body cream or skin lightening cream, which is a common misuse in Nigeria. Buy only from reputable pharmacies and look for known brands like Norbavate Plus Cream or Fexofyn Lotion to avoid fake products. Do not share your prescription cream with others, as their skin condition may be different and this cream can cause serious harm if misused.
Avoid using other steroid creams or ointments on the same area at the same time, as this can increase the risk of side effects. Be cautious if you are taking oral corticosteroids like prednisolone, as using both can increase overall steroid levels in your body. Let your doctor know if you are using any other medicated cream or skin treatment on the same area.
Check your specific combination
Is it safe to take Clobetasol with your other drugs?
Do not use this during pregnancy or breastfeeding unless your doctor specifically prescribes it, as strong steroids like clobetasol may harm the unborn baby or pass into breast milk.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be hot, so avoid leaving it in a car or near a window. Keep the cap tightly closed and store it out of the reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.