Flameon 1 mg/mL Injection Solution for injection (Buserelin) — Uses, Dosage & NAFDAC

Who is this for?

What is this drug?

Buserelin is a synthetic hormone that works by controlling the release of certain reproductive hormones in your body — it first briefly increases, then greatly reduces the production of hormones like estrogen and testosterone.

What is it used for?

Prostate cancerendometriosis (a condition where womb tissue grows outside the womb causing painful periods)uterine fibroidsinfertility treatment (used as part of IVF procedures)

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Fertility & Infertility

How it works

Binds to and activates GnRH receptors in the pituitary gland, causing initial elevation of LH and FSH; sustained exposure leads to receptor downregulation and suppression of gonadotropin release, resulting in decreased testosterone (in males) and estrogen (in females).

Prescription Required

You need a doctor's prescription to buy this drug.

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How to take this drug

Buserelin comes as an injection (like the Flameon 1 mg/mL brand) or a nasal spray. The injection is usually given under the skin (subcutaneous) by a healthcare professional. Dosage depends on your condition — for example, 0.5 mL (500 micrograms) injected three times daily for prostate cancer, or as directed by your doctor for fertility treatment. Always follow your doctor's specific instructions.

What if I Miss a Dose?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue your normal schedule. Do not double up. Contact your doctor if you miss multiple doses, as this can affect your treatment.

What to watch out for

Only use Flameon or any buserelin product prescribed by your doctor — do not buy from roadside vendors or unverified sources, as it requires proper cold storage. Do not stop treatment on your own even if you feel better or worse — your doctor needs to monitor your progress. Make sure you attend all follow-up appointments, as your doctor will need to check your hormone levels and response to the drug.

Common Side Effects

Hot flashes (sudden feeling of heat in the body)
headaches
mood swings or feeling emotional
reduced interest in sex
pain or redness at the injection site

Serious Side Effects

Difficulty breathing or swelling of the face and throat (allergic reaction) — go to the hospital immediately. Bone pain or trouble urinating (especially in prostate cancer patients in the first few weeks) — see your doctor urgently. Signs of depression or serious mood changes — tell your doctor right away.

Drug Interactions

Diabetes medicines — buserelin can affect blood sugar levels, so your doctor may need to adjust your diabetes medication. Drugs that affect heart rhythm (like some antibiotics or antimalaria drugs) — combining them with buserelin may increase the risk of heart problems. Always tell your doctor about every medicine you are taking, including herbal remedies.

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Pregnancy & Breastfeeding Warning

Buserelin is NOT safe during pregnancy or breastfeeding — it can harm the unborn baby, so women of childbearing age must confirm they are not pregnant before starting treatment.

Who Should NOT Take This

People allergic to buserelin or similar hormone drugs
pregnant or breastfeeding women
women with unexplained vaginal bleeding
and people with certain hormone-sensitive conditions not approved for this treatment should not use this drug.

How to Store

Store in a refrigerator (2–8°C) unless your pharmacist says otherwise. In Nigeria's hot climate, do not leave it out at room temperature for long. Keep it away from direct sunlight and heat. Always keep out of reach of children.

For information only — not medical advice. Always talk to a doctor or pharmacist before changing your medication.

Flameon 1 mg/mL Injection