Antidiarrheal and stomach protectant
Last reviewed July 2026
Who is this for?
Bismuth subsalicylate is a stomach medicine that works by coating the lining of your stomach and intestines, reducing inflammation, and killing some bacteria that cause stomach upset and diarrhea.
Inhibits prostaglandin-mediated intestinal secretion and reduces inflammatory cytokine production while the salicylate component provides antimicrobial activity against enteropathogens. Additionally, bismuth ions form a protective coating over the gastric mucosa, reducing acid-induced irritation and promoting healing of the gastrointestinal epithelium.
Available Over The Counter
Get this from any pharmacy or chemist: no prescription needed.
Explore this drug
This medicine is usually taken only when you have symptoms, not on a regular schedule. If you are using it regularly as directed by a doctor and you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue as normal.
Do not use this medicine for more than 2 days for diarrhea. If your running stomach continues, see a doctor as it could be something more serious like typhoid. Make sure you buy from a registered pharmacy and check the expiry date, not from roadside sellers. If you notice black stool, do not panic: it is a harmless side effect of the medicine, but if you also feel dizzy or weak, see a doctor.
Do not take it with blood thinners like warfarin or aspirin as it increases the risk of bleeding. Avoid taking it with tetracycline antibiotics (like doxycycline commonly used for infections in Nigeria) as it reduces their effectiveness: space them at least 2 hours apart. Avoid alcohol as it can worsen stomach irritation.
Check your specific combination
Is it safe to take Bismuth with your other drugs?
Bismuth subsalicylate is not safe during pregnancy, especially in the third trimester, and should be avoided while breastfeeding. Consult your doctor for a safer alternative.
Store in a cool, dry place away from direct sunlight and heat. Nigerian weather can be very hot, so avoid storing it in places like your car dashboard or near a window. Keep the bottle tightly closed and always keep it out of the reach of children.
For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.
Names this drug is sold under, especially in Nigerian and West African pharmacies
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Counterfeit Drug Warning
Fake drugs are a serious problem in Nigeria. Always buy from a registered pharmacy. If the packaging looks different from what is described above, do not use it.