How do you take Betamethasone dipropionate?

Apply a thin layer to the affected skin area once or twice daily. Gently rub it in until it disappears. Do not use more than your doctor recommends, and do not use it for longer than 2 to 4 weeks unless your doctor says so. Wash your hands after applying unless you are treating your hands.

What are the side effects of Betamethasone dipropionate?

Burning or stinging feeling when you first apply it, thinning of the skin after prolonged use, stretch marks on the skin, skin becoming lighter in colour at the application site, dryness or peeling of treated skin

Who should not take Betamethasone dipropionate?

People allergic to betamethasone or any steroid cream, people with skin infections like ringworm or boils (unless also using an antifungal or antibiotic), people with acne or rosacea, children under 12 without a doctor's prescription, and people with open wounds or broken skin.

Prescription

Topical corticosteroid (strong steroid skin medication)

Betamethasone dipropionate

Q: What is Betamethasone dipropionate used for?

Eczema, skin rashes, itchy skin, psoriasis (dry scaly patches on skin), dermatitis (skin inflammation), allergic skin reactions, insect bite reactions

Last reviewed July 2026

Who is this for?

For adults (18+). Standard adult dosing applies: see the How to Take tab for full instructions.

What is this drug?

Betamethasone dipropionate is a strong steroid cream or ointment that works by reducing swelling, redness, and itching on the skin. It calms down your body's immune response in the affected area to give you relief.

How it works

Binds to glucocorticoid receptors in the cytoplasm, translocating to the nucleus to suppress pro-inflammatory gene expression and inhibit phospholipase A2, thereby reducing production of inflammatory mediators (prostaglandins, leukotrienes) and decreasing local inflammation, erythema, and pruritus.

What is it used for?

Eczemaskin rashesitchy skinpsoriasis (dry scaly patches on skin)dermatitis (skin inflammation)allergic skin reactionsinsect bite reactions

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Skin Infections Allergies Eczema & Skin Rashes

Prescription Required

You need a doctor's prescription to buy this drug.

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What to watch out for

Do not use this cream as a skin-lightening or toning product, as this is a common misuse in Nigeria that causes serious skin damage including permanent thinning, stretch marks, and infections. Only buy from reputable pharmacies: products like Cleargee Cream and Zapit Cream should come in proper sealed packaging. Do not use on your face, groin, or armpits for extended periods unless your doctor specifically directs you to.

Common Side Effects

Burning or stinging feeling when you first apply it
thinning of the skin after prolonged use
stretch marks on the skin
skin becoming lighter in colour at the application site
dryness or peeling of treated skin

Serious Side Effects

If you notice your skin becoming very thin
cracked
or developing visible veins
stop using it and see a doctor immediately. If you develop signs of a skin infection like increased redness
pus
or worsening pain
seek medical attention right away.

Drug Interactions

Avoid using other steroid creams or ointments on the same area at the same time as this can increase side effects. Do not mix with skin-lightening or toning creams, as many Nigerian toning creams already contain steroids, and combining them can seriously damage your skin. Be cautious using it alongside medicated soaps or harsh skin products.

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Pregnancy & Breastfeeding Warning

Do not use during pregnancy or breastfeeding unless your doctor specifically prescribes it, as the steroid can be absorbed through your skin and may affect your baby.

Who Should NOT Take This

People allergic to betamethasone or any steroid cream
people with skin infections like ringworm or boils (unless also using an antifungal or antibiotic)
people with acne or rosacea
children under 12 without a doctor's prescription
and people with open wounds or broken skin.

How to Store

Store at room temperature below 30°C. Keep away from direct sunlight and heat: do not leave it on a window sill or in your car. Keep the tube tightly closed and away from children. Do not refrigerate unless the label says so.

For information only: not medical advice. Always talk to a doctor or pharmacist before changing your medication.